ReviewTherapeutic advances in neurological disorders2017
Differential diagnosis of neuromyelitis optica spectrum disorders.
Review in Therapeutic advances in neurological disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03819413 (Clinical Patterns of Neuromyelitis Optica Spectrum Disorders in Assiut University Hospital), which is not on this map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Patterns of Neuromyelitis Optica Spectrum Disorders in Assiut University Hospital
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.
- Consensus Recommendations for the Diagnosis and Treatment of Neuromyelitis Optica Spectrum Disorders (NMOSD): The MENACTRIMS Guidelines.CNS drugs · 2026Guideline
- Neuromyelitis optica spectrum disorder in an 11-year-old: a case report in a pediatric patient from Nepal.Annals of medicine and surgery (2012) · 2026Article
- Extensive Cerebral White Matter Involvement and Migrainous Headache in a Patient With Aquaporin-4-Positive NMOSD Mimicking CADASIL.Dementia and neurocognitive disorders · 2025Article
- Intractable Vomiting as an Initial and Evasive Presentation of Neuromyelitis Optica Spectrum Disorder.Cureus · 2025Article
- From Dengue to Demyelination: A Case of Brainstem Neuromyelitis Optica Spectrum Disorder Following Dengue Fever.Cureus · 2025Article
- Neuroborreliosis with encephalitis: a broad spectrum of clinical manifestations.BMC infectious diseases · 2025Article
- Longitudinal Extensive Transverse Myelitis After Respiratory Syncytial Virus Vaccination With Positive Anti-Recoverin Antibodies.Case reports in neurological medicine · 2025Article
- Assessing the effectiveness of machine learning and deep learning in differentiating neuroimmunological diseases: a systematic review and meta-analysis.Frontiers in neurology · 2025Article
- A Chinese girl with neuromyelitis optica spectrum disorder coexisting with primary Sjogren's syndrome: a case report and literature review.Frontiers in immunology · 2025Review
- Unusual clinical presentations in an aquaporin-4 antibody-positive patient: a case report.The Pan African medical journal · 2025Article
- Assessment of disability and disease burden in neuromyelitis optica spectrum disorders in the CIRCLES Cohort.Scientific reports · 2024Observational
- Neuromyelitis optica spectrum disorder co-existing with antiphospholipid syndrome: A case report.Clinical case reports · 2024Article
- Treatment and Rehabilitation of a Patient with Neuromyelitis Optica Spectrum Disorder-Induced Complete Spinal Cord Injury Following COVID-19 Vaccination: A Case Report.Journal of clinical medicine · 2024Article
- Prevalence of neuromyelitis optica spectrum disorder in the United States.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024Article
- Application and interpretation of core elements of the 2015 NMOSD diagnostic criteria in routine clinical practice.Frontiers in immunology · 2024Article
- Case report: Transition from anti-CD20 therapy to inebilizumab for 14 cases of neuromyelitis optica spectrum disorder.Frontiers in neurology · 2024Article
- Neuromyelitis Optica: Pathogenesis Overlap with Other Autoimmune Diseases.Current allergy and asthma reports · 2023Review
- A 28-Year-Old Woman With Left-Sided Weakness and Atypical MRI Lesions: From the National Multiple Sclerosis Society Case Conference Proceedings.Neurology(R) neuroimmunology & neuroinflammation · 2023Article
- Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis.Journal of neurology · 2023Review
- Adult-Onset Genetic Leukoencephalopathies With Movement Disorders.Journal of movement disorders · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder of the central nervous system (CNS) mostly manifesting as optic neuritis and/or myelitis, which are frequently recurrent/bilateral or longitudinally extensive, respectively. As the autoantibody to aquaporin-4 (AQP4-Ab) can mediate the pathogenesis of NMOSD, testing for the AQP4-Ab in serum of patients can play a crucial role in diagnosing NMOSD. Nevertheless, the differential diagnosis of NMOSD in clinical practice is often challenging despite the phenotypical and serological characteristics of the disease because: (1) diverse diseases with autoimmune, vascular, infectious, or neoplastic etiologies can mimic these phenotypes of NMOSD; (2) patients with NMOSD may only have limited clinical manifestations, especially in their early disease stages; (3) test results for AQP4-Ab can be affected by several factors such as assay methods, serologic status, disease stages, or types of treatment; (4) some patients with NMOSD do not have AQP4-Ab; and (5) test results for the AQP4-Ab may not be readily available for the acute management of patients. Despite some similarity in their phenotypes, these NMOSD and NMOSD-mimics are distinct from each other in their pathogenesis, prognosis, and most importantly treatment. Understanding the detailed clinical, serological, radiological, and prognostic differences of these diseases will improve the proper management as well as diagnosis of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.