Evidence map›Paper›PMID 28670325›Full record

ReviewFrontiers in genetics2017

More Is Better: Recent Progress in Multi-Omics Data Integration Methods.

Sijia Huang, Kumardeep Chaudhary, Lana X Garmire

Abstract readReview
In one paragraph

Review in Frontiers in genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 351 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
351citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

351 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Biological multi-omics approaches to next-generation biomarkers in immune-related disorders and malignancies: An overview.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  16. Integrative Analysis of Multimodal Omics Data.Annual review of statistics and its application · 2026
    Article
  17. ChatGPT in precision medicine.APL bioengineering · 2026
    Review
  18. Article
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  20. Review

291 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sijia HuangEpidemiology Program, University of Hawaii Cancer CenterHonolulu, HI, United States.
Kumardeep ChaudharyEpidemiology Program, University of Hawaii Cancer CenterHonolulu, HI, United States.
Lana X GarmireEpidemiology Program, University of Hawaii Cancer CenterHonolulu, HI, United States.

Funding

Transgenic Mouse, ICSI and IVF CoreP20GM103457 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI URSCHITZ, JOHANN · 2012 to 2018
$12.9M
An Integrative Omics Approach to Identify Biomarkers Related to Preeclampsia and Breast Cancer RisksR01HD084633 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARMIRE, LANA X · 2016 to 2020
$3.0M
Cancer precision medicine through spatially informative single cell image and transcriptomics data analysisR01LM012373 · NLM · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARMIRE, LANA X · 2016 to 2024
$2.4M
An Integrative Bioinformatics Approach to Study Single Cancer Cell HeterogeneityK01ES025434 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GARMIRE, LANA X · 2014 to 2018
$905k
NICHD NIH HHS R01 HD084633NIEHS NIH HHS K01 ES025434NIGMS NIH HHS P20 GM103457NLM NIH HHS R01 LM012373
6 · The paper itself

Abstract

Multi-omics data integration is one of the major challenges in the era of precision medicine. Considerable work has been done with the advent of high-throughput studies, which have enabled the data access for downstream analyses. To improve the clinical outcome prediction, a gamut of software tools has been developed. This review outlines the progress done in the field of multi-omics integration and comprehensive tools developed so far in this field. Further, we discuss the integration methods to predict patient survival at the end of the review.

Indexed as

integrationmulti-omicsprecision medicinepredictionprognosissupervised learningunsupervised learning

Identifiers

PMID28670325
PMCPMC5472696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.