ArticleIntestinal research2017
Familial aggregation of inflammatory bowel disease in patients with ulcerative colitis.
Article in Intestinal research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Translating IBD Genomics into Clinical Practice.Digestive diseases and sciences · 2026Review
- Inflammatory bowel disease phenotypes in diverse populations: a global comparative analysis.Journal of Crohn's & colitis · 2026Article
- Inflammatory bowel disease in south Asia: a scoping review.The lancet. Gastroenterology & hepatology · 2025Article
- Shared Pathophysiology of Inflammatory Bowel Disease and Psoriasis: Unraveling the Connection.Cureus · 2024Review
- Inflammatory bowel disease associated knowledge in South Indian populations: rational Study.African health sciences · 2023Article
- Does the road to primary prevention of inflammatory bowel disease start from childhood?JGH open : an open access journal of gastroenterology and hepatology · 2022Article
- Childhood antibiotics as a risk factor for Crohn's disease: The ENIGMA International Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2022Article
- Factors Affecting Ulcerative Colitis Flare-Ups: Associations With Smoking Habits and Other Patient Characteristics.Cureus · 2021Article
- Cross Talk between Gut Microbiota and Intestinal Mucosal Immunity in the Development of Ulcerative Colitis.Infection and immunity · 2021Review
- Inflammatory bowel disease: An Indian perspective.The Indian journal of medical research · 2021Review
- Familial aggregation of inflammatory bowel disease in India: prevalence, risks and impact on disease behavior.Intestinal research · 2019Article
- Is the emergence of inflammatory bowel disease a prime example of "the third epidemiological transition"?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2018Article
- Decreased Breg/Th17 Ratio Improved the Prognosis of Patients with Ulcerative Colitis.Canadian journal of gastroenterology & hepatology · 2018Article
- Epidemiology of Inflammatory Bowel Disease in India: The Great Shift East.Inflammatory intestinal diseases · 2017Review
- Familial and ethnic risk in inflammatory bowel disease.Annals of gastroenterologyReview
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsFamilial occurrence of inflammatory bowel disease (IBD) is well documented. Reports from Western countries have shown a higher familial occurrence of ulcerative colitis (UC) in first- and second-degree relatives than that in the Asian UC population. No data are currently available from the Indian subcontinent in this regard. We present our data on the familial aggregation of UC.
methodsRecords of patients with UC followed at the Inflammatory Bowel Disease Clinic at the All India Institute of Medical Sciences, New Delhi from August 2004 to January 2016 were reviewed. Details regarding the prevalence of family history and characteristics of these patients were recorded. Affected family members were contacted and disease characteristics were noted for assessment of familial aggregation.
resultsOf the 2,058 UC patients included in the analysis, a positive family history of IBD was confirmed in 31 patients (1.5%), 24 (77.4%) of whom had only first-degree relatives affected. All the affected relatives had UC and none had Crohn's disease. Among first-degree relatives, siblings were found to have the highest prevalence of IBD (53.3%), followed by parents (26.7%).
conclusionsThe probability of occurrence of IBD in family members of affected North Indian UC patients is lower than that reported in Western populations.
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