New Three-Component Bicyclization Leading to Densely Functionalized Pyrazolo[3,4-

Wen-Juan Hao, Peng Zhou, Fei-Yue Wu, Bo Jiang, Shu-Jiang Tu, Guigen Li

Abstract read

In one paragraph

Article in European journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Insights on Regioselective Synthesis of Fused Thiazoles: Density Functional Theory Calculations, Local Reactivity Indices, and Molecular Electrostatic Potential Analysis.ChemistryOpen · 2025
Article
Advances in pyrazolo[1,5-RSC advances · 2025
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wen-Juan HaoSchool of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, Jiangsu 221116, (China).

Peng ZhouSchool of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, Jiangsu 221116, (China).

Fei-Yue WuSchool of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, Jiangsu 221116, (China).

Bo JiangSchool of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, Jiangsu 221116, (China).

Shu-Jiang TuSchool of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, Jiangsu 221116, (China).

Guigen LiDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, United States.

Funding

GAP Chemistry Approaches to Chiral Amino Acids, Peptides and PeptidomimeticsR33DA031860 · NIDA · TEXAS TECH UNIVERSITY · PI LI, GUIGEN · 2013 to 2014

$706k

NIDA NIH HHS R33 DA031860

6 · The paper itself

Abstract

A novel three-component bicyclization for the efficient synthesis of densely functionalized pyrazolo[3,4-

Indexed as

BicyclizationMicrowave HeatingMulticomponent ReactionsPyrazolo[3,4-d]thiazolo[3,2-a]pyrimidinesα-thiocyanate ketones

Identifiers

PMID28670172

DOI10.1002/ejoc.201600163

PMCPMC5489242

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.