Evidence map›Paper›PMID 28669936›Full record

ArticleEnvironmental health perspectives2017

Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children.

Olena Gruzieva, Simon Kebede Merid, Anna Gref, Ashwini Gajulapuri, Nathanaël Lemonnier, Stéphane Ballereau, Bruna Gigante, Juha Kere, Charles Auffray, Erik Melén and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
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  11. Clinical and inflammatory features of traffic-related diesel exposure in children with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Review
  18. Air pollution, metabolites and respiratory health across the life-course.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Olena GruzievaInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Simon Kebede MeridInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Anna GrefInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Ashwini GajulapuriInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Nathanaël LemonnierEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, Université de Lyon, Lyon, France
Stéphane BallereauEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, Université de Lyon, Lyon, France
Bruna GiganteInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Juha KereDepartment of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
Charles AuffrayEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, Université de Lyon, Lyon, France
Erik MelénInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Göran PershagenInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Karolinska Institutet · SEUniversité Claude Bernard Lyon 1 · FRStockholm County Council · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term exposure to ambient air pollution can lead to adverse health effects in children; however, underlying biological mechanisms are not fully understood.

objectivesWe evaluated the effect of air pollution exposure during different time periods on mRNA expression as well as circulating levels of inflammatory cytokines in children.

methodsWe measured a panel of 10 inflammatory markers in peripheral blood samples from 670 8-y-old children in the Barn/Child, Allergy, Milieu, Stockholm, Epidemiology (BAMSE) birth cohort. Outdoor concentrations of nitrogen dioxide (NO

resultsA 10 μg/m

conclusionOur results indicate alterations in systemic inflammatory markers in 8-y-old children in relation to early-life exposure to traffic-related air pollution. https://doi.org/10.1289/EHP460.

Indexed as

Air PollutionBiomarkersChildCytokinesEnvironmental ExposureGene ExpressionHumansHypersensitivityInterleukin-10Interleukin-6Nitrogen DioxideParticulate MatterVehicle EmissionsBiomarkersCytokinesInterleukin-10Interleukin-6Nitrogen DioxideParticulate MatterVehicle Emissions

Identifiers

PMID28669936
PMCPMC5714301
OpenAlexW2733867537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.