Evidence map›Paper›PMID 28668927›Full record

ArticleAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2017

Delirium After Transcatheter Aortic Valve Replacement.

Jennifer L Giuseffi, Nyal E Borges, Leanne M Boehm, Li Wang, John A McPherson, Joseph L Fredi, Rashid M Ahmad, E Wesley Ely, Pratik P Pandharipande

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer L GiuseffiJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Nyal E BorgesJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee. nyalborges@gmail.com.
Leanne M BoehmJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Li WangJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.
John A McPhersonJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Joseph L FrediJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Rashid M AhmadJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.
E Wesley ElyJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Pratik P PandharipandeJennifer L. Giuseffi is a cardiologist, Division of Cardiovascular Medicine, WellStar Medical Group, Marietta, Georgia. Nyal E. Borges is an internal medicine chief resident, Division of General Internal Medicine, Department of Medicine, Leanne M. Boehm is a research nurse, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Li Wang is a statistician, Department of Biostatistics, John A. McPherson is an interventional cardiologist and professor of medicine, Joseph L. Fredi is an interventional cardiologist and assistant professor of medicine, Division of Cardiovascular Medicine, Rashid M. Ahmad is a cardiothoracic surgeon, Division of Cardiothoracic Surgery, Department of Medicine, Pratik P. Pandharipande is a professor of anesthesiology and surgery, Division of Anesthesiology Critical Care Medicine, Department of Anesthesiology, and E. Wesley Ely is a professor of medicine, Division of Allergy and Pulmonary Critical Care, Department of Medicine, and Center for Health Science Research, Vanderbilt University Medical Center, Nashville, Tennessee.

Funding

The MIND USA StudyR01AG035117 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ELY, E WESLEY · 2011 to 2016
$7.3M
Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe SepsisR01HL111111 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PANDHARIPANDE, PRATIK · 2012 to 2017
$3.7M
The MIND ICU StudyR01AG027472 · NIA · VANDERBILT UNIVERSITY · PI ELY, E WESLEY · 2006 to 2010
$3.0M
NHLBI NIH HHS R01 HL111111NIA NIH HHS R01 AG027472NIA NIH HHS R01 AG035117
6 · The paper itself

Abstract

backgroundPostoperative delirium is associated with increased mortality. Patients undergoing transcatheter aortic valve replacement are at risk for delirium because of comorbid conditions.

objectiveTo compare the incidence, odds, and mortality implications of delirium between patients undergoing transcatheter replacement and patients undergoing surgical replacement.

methodsThe Richmond Agitation-Sedation Scale and the Confusion Assessment Method for the Intensive Care Unit were used to assess arousal level and delirium prospectively in all patients with severe aortic stenosis who had transcatheter or surgical aortic valve replacement at an academic medical center. Multivariable logistic regression was used to determine the relationship between procedure type and occurrence of delirium. Cox regression was used to assess the association between postoperative delirium and 6-month mortality.

resultsA total of 105 patients had transcatheter replacement and 121 had surgical replacement. Patients in the transcatheter group were older (median age, 81 vs 68 years;

conclusionsDelirium occurs in at least 1 in 5 patients after transcatheter or surgical aortic valve replacement. Delirium is less likely to develop in the transcatheter group but is associated with higher mortality in both groups.

Indexed as

AgedAged, 80 and overAortic Valve StenosisComorbidityDeliriumFemaleHeart Valve Prosthesis ImplantationHumansIncidenceMaleMiddle AgedPostoperative ComplicationsProportional Hazards ModelsProspective StudiesTranscatheter Aortic Valve Replacement

Identifiers

PMID28668927
PMCPMC7393791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.