Evidence map›Paper›PMID 28668343›Full record

ArticleNeuroImage2019

Changes in arterial cerebral blood volume during lower body negative pressure measured with MRI.

Joseph R Whittaker, Molly G Bright, Ian D Driver, Adele Babic, Sharmila Khot, Kevin Murphy

Open access · hybridAbstract read
In one paragraph

Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Elevated cerebral blood flow in patients with pure autonomic failure.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Article
  5. Rude mechanicals in brain haemodynamics: non-neural actors that influence blood flow.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  6. Article
  7. Review
  8. Article
  9. Rebuttal from David Simpson and Jurgen Claassen.The Journal of physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joseph R WhittakerCardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff CF24 4HQ, United Kingdom; Cardiff University Brain Research Imaging Centre (CUBRIC), School of Physics and Astronomy, Cardiff University, Queen's Buildings, The Parade, Cardiff CF24 3AA, United Kingdom. Electronic address: whittakerj3@cardiff.ac.uk.
Molly G BrightSir Peter Mansfield Imaging Centre, School of Medicine, University of Nottingham, Nottingham NG7 2RD, United Kingdom; Division of Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, United Kingdom.
Ian D DriverCardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff CF24 4HQ, United Kingdom.
Adele BabicDepartment of Anaesthesia and Intensive Care Medicine, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom.
Sharmila KhotDepartment of Anaesthesia and Intensive Care Medicine, Cardiff University School of Medicine, Cardiff CF14 4XN, United Kingdom.
Kevin MurphyCardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff CF24 4HQ, United Kingdom; Cardiff University Brain Research Imaging Centre (CUBRIC), School of Physics and Astronomy, Cardiff University, Queen's Buildings, The Parade, Cardiff CF24 3AA, United Kingdom.
Cardiff University · GBUniversity of Nottingham · GB

Funding

Wellcome Trust 200804/Z/16/ZWellcome Trust WT090199Wellcome Trust WT200804
6 · The paper itself

Abstract

Cerebral Autoregulation (CA), defined as the ability of the cerebral vasculature to maintain stable levels of blood flow despite changes in systemic blood pressure, is a critical factor in neurophysiological health. Magnetic resonance imaging (MRI) is a powerful technique for investigating cerebrovascular function, offering high spatial resolution and wide fields of view (FOV), yet it is relatively underutilized as a tool for assessment of CA. The aim of this study was to demonstrate the potential of using MRI to measure changes in cerebrovascular resistance in response to lower body negative pressure (LBNP). A Pulsed Arterial Spin Labeling (PASL) approach with short inversion times (TI) was used to estimate cerebral arterial blood volume (CBV

Indexed as

Cerebral Blood VolumeCerebrovascular CirculationLower Body Negative PressureArteriesCerebral CortexHomeostasisHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleSpin LabelsSpin LabelsArterial spin labelingCerebral autoregulationCerebral blood volumeLower body negative pressureMagnetic resonance imaging

Identifiers

PMID28668343
PMCPMC6414398
OpenAlexW2727726256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.