Evidence map›Paper›PMID 28668230›Full record

ArticleThe Lancet. Global health2017

Global funding trends for malaria research in sub-Saharan Africa: a systematic analysis.

Michael G Head, Sian Goss, Yann Gelister, Victor Alegana, Rebecca J Brown, Stuart C Clarke, Joseph R A Fitchett, Rifat Atun, J Anthony G Scott, Marie-Louise Newell and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Lancet. Global health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Scooping Review of Diabetes Research in Kenya from 2000 to 2020.The East African health research journal · 2024
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  17. Vaccines · 2021
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Michael G HeadGlobal Health Research Institute and Faculty of Medicine, University of Southampton, Southampton, UK. Electronic address: m.head@soton.ac.uk.
Sian GossGlobal Health Research Institute and Faculty of Medicine, University of Southampton, Southampton, UK; WorldPop, Department of Geography and Environment, University of Southampton, Southampton, UK.
Yann GelisterGlobal Health Research Institute and Faculty of Medicine, University of Southampton, Southampton, UK.
Victor AleganaWorldPop, Department of Geography and Environment, University of Southampton, Southampton, UK.
Rebecca J BrownGlobal Health Research Institute and Faculty of Medicine, University of Southampton, Southampton, UK.
Stuart C ClarkeGlobal Health Research Institute and Faculty of Medicine, University of Southampton, Southampton, UK; Southampton NIHR Respiratory Biomedical Research Unit, Southampton General Hospital, Southampton, UK.
Joseph R A FitchettHarvard TH Chan School of Public Health, Harvard University, Boston, MA, USA.
Rifat AtunHarvard TH Chan School of Public Health, Harvard University, Boston, MA, USA.
J Anthony G ScottDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Marie-Louise NewellGlobal Health Research Institute and Faculty of Medicine, University of Southampton, Southampton, UK.
Sabu S PadmadasDepartment of Social Statistics and Demography and Centre for Global Health, Population, Poverty and Policy, University of Southampton, Southampton, UK.
Andrew J TatemWorldPop, Department of Geography and Environment, University of Southampton, Southampton, UK; Flowminder Foundation, Stockholm, Sweden.

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joaniter Immaculate Nankabirwa · 2010 to 2026
$29.3M
NIAID NIH HHS U19 AI089674Wellcome Trust
6 · The paper itself

Abstract

backgroundTotal domestic and international funding for malaria is inadequate to achieve WHO global targets in burden reduction by 2030. We describe the trends of investments in malaria-related research in sub-Saharan Africa and compare investment with national disease burden to identify areas of funding strength and potentially neglected populations. We also considered funding for malaria control.

methodsResearch funding data related to malaria for 1997-2013 were sourced from existing datasets, from 13 major public and philanthropic global health funders, and from funding databases. Investments (reported in US$) were considered by geographical area and compared with data on parasite prevalence and populations at risk in sub-Saharan Africa. 45 sub-Saharan African countries were ranked by amount of research funding received.

findingsWe found 333 research awards totalling US$814·4 million. Public health research covered $308·1 million (37·8%) and clinical trials covered $275·2 million (33·8%). Tanzania ($107·8 million [13·2%]), Uganda ($97·9 million [12·0%]), and Kenya ($92·9 million [11·4%]) received the highest sum of research investment and the most research awards. Malawi, Tanzania, and Uganda remained highly ranked after adjusting for national gross domestic product. Countries with a reasonably high malaria burden that received little research investment or funding for malaria control included Central African Republic (ranked 40th) and Sierra Leone (ranked 35th). Congo (Brazzaville) and Guinea had reasonably high malaria mortality, yet Congo (Brazzaville) ranked 38th and Guinea ranked 25th, thus receiving little investment.

interpretationSome countries receive reasonably large investments in malaria-related research (Tanzania, Kenya, Uganda), whereas others receive little or no investments (Sierra Leone, Central African Republic). Research investments are typically highest in countries where funding for malaria control is also high. Investment strategies should consider more equitable research and operational investments across countries to include currently neglected and susceptible populations.

fundingRoyal Society of Tropical Medicine and Hygiene and Bill & Melinda Gates Foundation.

Indexed as

MalariaAfrica South of the SaharaClinical Trials as TopicFinancing, GovernmentFund RaisingGlobal HealthHumansInvestmentsPublic HealthResearchResearch Support as Topic

Identifiers

PMID28668230
PMCPMC5567191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.