SynthesisJournal of genetic counseling2017
Family Communication, Risk Perception and Cancer Knowledge of Young Adults from BRCA1/2 Families: a Systematic Review.
Synthesis in Journal of genetic counseling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- A systematic review of theory-informed strategies used in interventions fostering family genetic risk communication.Patient education and counseling · 2022Pooled it
- Cancer Predisposition Genes in Adolescents and Young Adults (AYAs): a Review Paper from the Italian AYA Working Group.Current oncology reports · 2022Pooled it
- Chatbot Intervention and Cancer Risk Knowledge in Adolescents and Young Adults With Cancer Predisposition: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Evaluating a communication aid for return of genetic results in families with hypertrophic cardiomyopathy: A randomized controlled trial.Journal of genetic counseling · 2023Trial
- Perceived usefulness of online videos for hereditary breast cancer communication in Japan: Patient and provider perspectives.Public health in practice (Oxford, England) · 2026Article
- Psychosocial aspects of RUNX1-familial platelet disorder in adolescents and young adults: "The fear of knowing it could happen sometime down the road".Journal of genetic counseling · 2026Article
- Understanding risk perception and risk-reducing decision-making for surgery among individuals with a genetic predisposition to epithelial ovarian cancer.Journal of genetic counseling · 2026Article
- Article
- Development and pilot testing of AYA-RISE, a risk information and screening education intervention for adolescents and young adults with cancer risk syndromes.Familial cancer · 2026Article
- Prospective changes in primary care patients' family communication after skin cancer genetic test offer.PEC innovation · 2025Article
- A knowledge, attitudes, and practices study on BRCA mutations among family members of women diagnosed with epithelial ovarian or fallopian tube cancer.Obstetrics & gynecology science · 2025Article
- BRCA cascade counselling and testing in Italy: current position and future directions.BMC cancer · 2025Observational
- Need for specially designed educational support groups: Young women's experiences of being identified with BRCA pathogenic variants.Journal of genetic counseling · 2025Article
- Exploring women's knowledge and their perception of risk of uterine cancer in Lagos, Nigeria: a multi-facility based cross-sectional study.Ecancermedicalscience · 2025Article
- Information needs persist after genetic counseling and testing for BRCA1/2 and Lynch Syndrome.Breast cancer research and treatment · 2024Article
- Health-related roles of older generations in families with inherited genetic conditions: a scoping review.Journal of community genetics · 2024Article
- An exploration of knowledge, risk perceptions, and communication in a family with multiple genetic risks for Parkinson's disease.Journal of genetic counseling · 2023Article
- Impact of genomic literacy components on genetic testing decision-making in the general Japanese population in the 20s and 30s.PloS one · 2023Article
- Psychological Determinants of Men's Adherence to Cascade Screening forCurrent oncology (Toronto, Ont.) · 2022Article
- Information needs on breast cancer genetic and non-genetic risk factors in relatives of women with a BRCA1/2 or PALB2 pathogenic variant.Breast (Edinburgh, Scotland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding challenges in familial communication of cancer risk has informed genetic service delivery. Parent-child interactions have received considerable attention, but few studies focus on young adulthood experiences within BRCA1/2 families. Young adults are approaching, or at a life stage where awareness of hereditary cancer risk is vital for informed choice of risk management options. This review assesses family communication, risk perception and cancer knowledge held by 18-40 year old individuals who have a parent with a BRCA1/2 gene mutation or carry the gene mutation themselves. Thirteen papers met the inclusion criteria. One utilized a 'mixed methods' methodology and the remaining used a qualitative approach. Findings were synthesized into themes and reported narratively. In general, parents are communicating openly about genetic risk with young adult offspring, but there is evidence that some young adults are withholding information from their parents about their own test results. Risk perception is influenced by a family history of cancer, childbearing plans and health providers' advice. Misconceptions about genetic risk appear to be common and gaps in hereditary cancer knowledge are evident. It is unclear whether incorrect knowledge was passed from parents to offspring. Health providers need to provide developmentally appropriate services for emerging adults (18-25 years old), with particular support in navigating through risk management options.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.