SynthesisInternational journal of colorectal disease2017
Colorectal cancer surgery in the very elderly patient: a systematic review of laparoscopic versus open colorectal resection.
Synthesis in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 149 citations in OpenAlex.
- EAES/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults.Surgical endoscopy · 2024Guideline
- Laparoscopic liver resection in elderly patients: systematic review and meta-analysis.Surgical endoscopy · 2019Pooled it
- Long-term results of a randomized study comparing open surgery and laparoscopic surgery in elderly colorectal cancer patients (Eld Lap study).Surgical endoscopy · 2021Trial
- Laparoscopic surgery should be a viable option for T4 colon cancer: evidence from a propensity score matching analysis.Updates in surgery · 2026Observational
- Real-World Results of Curative Open Colorectal Cancer Surgery in Octogenarians: Long-Term Survival Despite High Frailty Burden.Medical sciences (Basel, Switzerland) · 2026Observational
- Minimally invasive surgical resection reduces one-year mortality, especially in high-risk colon cancer patients: an emulated trial.EClinicalMedicine · 2026Article
- Development and validation of a risk prediction model for major postoperative adverse events in elderly colon cancer using firth regression: a large-scale retrospective study.Frontiers in oncology · 2026Article
- Days alive and out of hospital at 90 days as a composite outcome measure in patients undergoing elective surgery for colorectal cancer- a nationwide, observational study.BMC gastroenterology · 2025Observational
- Management of rectal prolapse in octogenarians: lesson learned in 13 years' experience from a high-volume center.Updates in surgery · 2025Article
- Surgical treatment strategy for elderly patients with esophageal cancer in the new era: a narrative review.Surgery today · 2025Review
- Surgical outcomes and patient selection in nonagenarians with colon cancer: a comparative multi-institutional study of laparoscopic and open approaches.Langenbeck's archives of surgery · 2025Article
- Article
- Integration of near-infrared fluorescence imaging and Sonazoid contrast-enhanced ultrasound in laparoscopic resection of colorectal liver metastases: a dual-center retrospective study.Surgical endoscopy · 2025Article
- Review
- Retrospective analysis of curative rectal cancer surgery outcomes in elderly patients.Scientific reports · 2025Article
- Impact of autonomic nerve-oriented anatomical laparoscopic surgery on recovery in patients with colorectal cancer.World journal of gastrointestinal surgery · 2025Article
- Short-term efficacy of laparoscopic radical resection for colorectal cancer and risk of unplanned reoperation after surgery.World journal of gastrointestinal surgery · 2025Article
- Article
- Short- and long-term outcomes of laparoscopic right hemicolectomy with D3 resection for right colon cancer in elderly patients.Langenbeck's archives of surgery · 2024Article
- Complications and comorbidities associated with antineoplastic chemotherapy: Rethinking drug design and delivery for anticancer therapy.Acta pharmaceutica Sinica. B · 2024Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionColorectal cancer is the second most common cause of death from neoplastic disease in men and third in women of all ages. Globally, life expectancy is increasing, and consequently, an increasing number of operations are being performed on more elderly patients with the trend set to continue. Elderly patients are more likely to have cardiovascular and pulmonary comorbidities that are associated with increased peri-operative risk. They further tend to present with more locally advanced disease, more likely to obstruct or have disseminated disease. The aim of this review was to investigate the feasibility of laparoscopic colorectal resection in very elderly patients, and whether there are benefits over open surgery for colorectal cancer.
methodsA systematic literature search was performed on Medline, Pubmed, Embase and Google Scholar. All comparative studies evaluating patients undergoing laparoscopic versus open surgery for colorectal cancer in the patients population over 85 were included. The primary outcomes were 30-day mortality and 30-day overall morbidity. Secondary outcomes were operating time, time to oral diet, number of retrieved lymph nodes, blood loss and 5-year survival.
resultsThe search provided 1507 citations. Sixty-nine articles were retrieved for full text analysis, and only six retrospective studies met the inclusion criteria. Overall mortality for elective laparoscopic resection was 2.92% and morbidity 23%. No single study showed a significant difference between laparoscopic and open surgery for morbidity or mortality, but pooled data analysis demonstrated reduced morbidity in the laparoscopic group (p = 0.032). Patients undergoing laparoscopic surgery are more likely to have a shorter hospital stay and a shorter time to oral diet.
conclusionElective laparoscopic resection for colorectal cancer in the over 85 age group is feasible and safe and offers similar advantages over open surgery to those demonstrated in patients of younger ages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.