Evidence map›Paper›PMID 28667269›Full record

ArticleScientific reports2017

Novel carbon quantum dots from egg yolk oil and their haemostatic effects.

Yan Zhao, Yue Zhang, Xiaoman Liu, Hui Kong, Yongzhi Wang, Gaofeng Qin, Peng Cao, Xingxing Song, Xin Yan, Qingguo Wang and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Protective effects ofFrontiers in pharmacology · 2023
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yan ZhaoSchool of Basic Medical Sciences, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Yue ZhangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Xiaoman LiuSchool of Basic Medical Sciences, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Hui KongSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Yongzhi WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Gaofeng QinSchool of Basic Medical Sciences, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Peng CaoSchool of Basic Medical Sciences, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Xingxing SongSchool of Basic Medical Sciences, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Xin YanSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Qingguo WangSchool of Basic Medical Sciences, Beijing University of Chinese Medicine, Chaoyang, Qu, China.
Huihua QuCenter of Scientific Experiment, Beijing University of Chinese Medicine, Chaoyang, Qu, China. quhuihuadr@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the properties of egg yolk oil (EYO) were investigated. Water extraction, dialysis, and ultrafiltration were used to extract and purify EYO, and microscopy, spectrophotometry, and chromatography were used to identify carbon dots (CDs) present in EYO (EYO CDs). Morphology analyses demonstrated that CDs were almost spherical, with an average size of <10 nm, a lattice spacing of 0.267 nm, and a composition of mainly C, O, and Fe. The solution showed bright blue fluorescence at 365 nm. Tail haemorrhaging and liver haemorrhaging experiments showed that CD-treated mice had significantly shorter bleeding times than did control mice. Coagulation assays suggested that EYO CDs stimulate the intrinsic blood coagulation system and activate the fibrinogen system. Thus, EYO CDs possess the ability to activate haemostasis, which may lead to further investigations of this ingredient of traditional Chinese medicine.

Indexed as

AnimalsCarbonEgg YolkHemostasisHemostaticsMaleMiceQuantum DotsCarbonHemostatics

Identifiers

PMID28667269
PMCPMC5493685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.