Evidence map›Paper›PMID 28667200›Full record

Observational studyBMJ open2017

Quality of life, treatment satisfaction and efficacy of non-biological systemic therapies in patients with plaque psoriasis: study protocol for a prospective observational study.

Christine Fink, Timo E Schank, Nina Trenkler, Lorenz Uhlmann, Knut Schäkel

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christine FinkDepartment of Dermatology, University of Heidelberg, Heidelberg, Germany.
Timo E SchankDepartment of Dermatology, University of Heidelberg, Heidelberg, Germany.
Nina TrenklerDepartment of Dermatology, University of Heidelberg, Heidelberg, Germany.
Lorenz UhlmannInstitute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany.
Knut SchäkelDepartment of Dermatology, University of Heidelberg, Heidelberg, Germany.
Heidelberg University · DEZimmer Biomet (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPsoriasis vulgaris often leads to a significant impaired quality of life and dissatisfaction with the existing therapeutic approaches. However, patients' quality of life and treatment satisfaction are of utmost importance, since it is positively related to therapy adherence and encourages patient's compliance. The study described herein evaluates the quality of life, treatment satisfaction and efficacy during the initial 6 months of treatment with a non-biological systemic agent in a real-life clinical setting. METHODS AND ANALYSIS: This observational study compares quality of life, treatment satisfaction and the efficacy of non-biological systemic therapy between 60 patients suffering from plaque psoriasis receiving the non-biological systemic therapies with apremilast, methotrexate and fumaric acid esters. ETHICS AND DISSEMINATION: Ethics approval was provided by the ethics committee of the medical faculty of the University of Heidelberg. Ethics approval number is S-298/2015. The design and the final results of the study will be published and made available to the public. TRIAL REGISTRATION NUMBER: German Clinical Trial Register (DRKS): DRKS00008721 (https://www.germanctr.de/).

Indexed as

Patient SatisfactionQuality of LifeAdultAnti-Inflammatory Agents, Non-SteroidalDermatologic AgentsFumaratesHumansMethotrexatePatient CompliancePersonal SatisfactionPilot ProjectsProspective StudiesPsoriasisThalidomideAnti-Inflammatory Agents, Non-SteroidalapremilastDermatologic AgentsFumaratesMethotrexateThalidomideapremilastefficacyfumaric acid estersmethotrexatenon-biologic systemic therapiesotezlaPsoriasisquality of lifetreatment satisfaction

Identifiers

PMID28667200
PMCPMC5734296
OpenAlexW2734702263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.