Evidence map›Paper›PMID 28667014›Full record

ArticleThe Journal of biological chemistry2017

The gluconate shunt is an alternative route for directing glucose into the pentose phosphate pathway in fission yeast.

Mark E Corkins, Stevin Wilson, Jean-Christophe Cocuron, Ana P Alonso, Amanda J Bird

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Metabolic Responses ofPlants (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Metabolites · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Mark E CorkinsFrom the Department of Molecular Genetics.
Stevin WilsonFrom the Department of Molecular Genetics.
Jean-Christophe CocuronFrom the Department of Molecular Genetics.
Ana P AlonsoFrom the Department of Molecular Genetics.
Amanda J BirdFrom the Department of Molecular Genetics, bird.96@osu.edu.ORCID 0000-0002-1846-7050
Laboratory of Molecular Genetics · PLPlanta · RUUnité de Nutrition Humaine · FR

Funding

Zinc-dependent regulation of gene expressionR01GM105695 · NIGMS · OHIO STATE UNIVERSITY · PI BIRD, AMANDA JANE · 2014 to 2018
$1.4M
NIGMS NIH HHS R01 GM105695
6 · The paper itself

Abstract

Glycolysis and the pentose phosphate pathway both play a central role in the degradation of glucose in all domains of life. Another metabolic route that can facilitate glucose breakdown is the gluconate shunt. In this shunt glucose dehydrogenase and gluconate kinase catalyze the two-step conversion of glucose into the pentose phosphate pathway intermediate 6-phosphogluconate. Despite the presence of these enzymes in many organisms, their only established role is in the production of 6-phosphogluconate for the Entner-Doudoroff pathway. In this report we performed metabolic profiling on a strain of

Indexed as

Pentose Phosphate PathwayEnergy MetabolismGene DeletionGluconatesGlucose DehydrogenasesGlucosephosphate DehydrogenaseMetabolomicsPhosphotransferases (Alcohol Group Acceptor)Recombinant ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsTranscription FactorsGcd1 protein, S pombeGluconatesgluconic acidgluconokinaseGlucose DehydrogenasesGlucosephosphate DehydrogenaseIdn1 protein, S pombeLoz1 protein, S pombePhosphotransferases (Alcohol Group Acceptor)Recombinant ProteinsSchizosaccharomyces pombe ProteinsTranscription FactorsZwf1 protein, S pombegene expressiongluconateglucose degradationglucose metabolismNADPH regenerationpentose phosphate pathway (PPP)secondary metabolismzinc

Identifiers

PMID28667014
PMCPMC5566534
OpenAlexW2724527698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.