Evidence map›Paper›PMID 28666772›Full record

Trial reportJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2017

Relationship among clinical factors in childhood intermittent exotropia.

Rosanne Superstein, Trevano W Dean, Jonathan M Holmes, Danielle L Chandler, Susan A Cotter, David K Wallace, B Michele Melia, Raymond T Kraker, R Grey Weaver, Brian G Mohney and 3 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  8. Observational
  9. Article
  10. Article
  11. Article
  12. Characterization of Intelligence in Children with Exotropia.International journal of environmental research and public health · 2019
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Rosanne SupersteinCentre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada. Electronic address: pedig@jaeb.org.
Trevano W DeanJaeb Center for Health Research, Tampa, Florida.
Jonathan M HolmesMayo Clinic, Rochester, Minnesota.
Danielle L ChandlerJaeb Center for Health Research, Tampa, Florida.
Susan A CotterSouthern California College of Optometry at Marshall B. Ketchum University, Fullerton, California.
David K WallaceDuke Eye Center, Durham, North Carolina.
B Michele MeliaJaeb Center for Health Research, Tampa, Florida.
Raymond T KrakerJaeb Center for Health Research, Tampa, Florida.
R Grey WeaverDepartment of Ophthalmology, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Brian G MohneyMayo Clinic, Rochester, Minnesota.
Sean P DonahueVanderbilt Eye Center, Nashville, Tennessee.
Eileen E BirchRetina Foundation of the Southwest, Dallas, Texas.
Pediatric Eye Disease Investigator Group
Jaeb Center for Health Research · USMayo Clinic · USCentre Hospitalier Universitaire Sainte-Justine · CAMarshall B. Ketchum University · USRetina Foundation of the Southwest · USVanderbilt Health · USWake Forest University · US

Funding

Pediatric Eye Disease Investigator Group Coordinating CenterU10EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI KRAKER, RAYMOND · 1997 to 2018
$75.2M
Pediatric Eye Disease Investigator Group NetworkUG1EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI Raymond Kraker, Stacy Pineles · 2019 to 2026
$53.7M
Pediatric Eye Disease Investigator Group: Chair's OfficeU10EY018810 · NEI · MAYO CLINIC ROCHESTER · PI HOLMES, JONATHAN M · 2009 to 2013
$3.5M
PEDIATRIC EYE DISEASE INVESTIGATOR GROUP: CHAIR'S OFFICEU10EY023198 · NEI · INDIANA UNIVERSITY INDIANAPOLIS · PI WALLACE, DAVID K · 2014 to 2018
$1.4M
NEI NIH HHS U10 EY011751NEI NIH HHS U10 EY018810NEI NIH HHS U10 EY023198NEI NIH HHS UG1 EY011751
6 · The paper itself

Abstract

purposeTo determine the relationships between stereoacuity, control of exotropia, and angle of deviation in children with intermittent exotropia (IXT).

methodsData collected for 652 participants 3 to <11 years of age with IXT meeting eligibility criteria for enrollment into one of two multicenter, randomized clinical trials were used to evaluate relationships between stereoacuity, control, and angle of deviation at enrollment.

resultsAny level of stereoacuity and angle of deviation could be accompanied by any level of control. Worse distance exotropia control was weakly associated with poorer distance stereoacuity (R = 0.26; 99% CI, 0.17-0.36) and larger angles of deviation at distance (R = 0.27; 99% CI, 0.17-0.36). Worse near exotropia control was weakly associated with poorer near stereoacuity (R = 0.17; 99% CI, 0.07-0.27) and moderately associated with larger angles of deviation at near (R = 0.37; 99% CI, 0.28-0.45). There was no association between stereoacuity and angle of deviation at distance (R = 0.07; 99% CI, -0.03 to 0.17) or at near (R = 0.02; 99% CI, -0.08 to 0.12).

conclusionsAlthough weak and moderate associations were found between stereoacuity, control, and angle of deviation, a child may exhibit any combination of stereoacuity, control, and angle of deviation. The specific roles of control, stereoacuity, and angle of deviation in the diagnosis, management, and pathogenesis of IXT are unclear, and each appears to yield somewhat independent information.

Indexed as

Analysis of VarianceAnisometropiaChildChild, PreschoolDepth PerceptionExotropiaFemaleFixation, OcularHumansMaleVisual Acuity

Identifiers

PMID28666772
PMCPMC5656234
OpenAlexW2730161120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.