Evidence map›Paper›PMID 28666575›Full record

ReviewMedicina (Kaunas, Lithuania)2017

Alternans in atria: Mechanisms and clinical relevance.

Giedrius Kanaporis, Lothar A Blatter

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Activation of Small Conductance CaInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Differences in Effects of Length-Dependent Regulation of Force and CaInternational journal of molecular sciences · 2023
    Article
  7. Targeted Atrial Fibrillation Therapy and Risk Stratification Using Atrial Alternans.Journal of cardiovascular development and disease · 2023
    Review
  8. Article
  9. Interleukin-6-Mediated-CaFrontiers in immunology · 2021
    Article
  10. Article
  11. Mitochondrial calcium uniporter complex activation protects against calcium alternans in atrial myocytes.American journal of physiology. Heart and circulatory physiology · 2020
    Article
  12. Electrocardiographic features of patients with COVID-19 pneumonia.European journal of internal medicine · 2020
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giedrius KanaporisDepartment of Physiology & Biophysics, Rush University Medical Center, Chicago, USA. Electronic address: giedrius_kanaporis@rush.edu.
Lothar A BlatterDepartment of Physiology & Biophysics, Rush University Medical Center, Chicago, USA.

Funding

Program AdministrationP01HL080101 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERS, DONALD M · 2006 to 2015
$23.4M
Limiting Pathological Calcium Induced Calcium Release in HeartR01HL057832 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI FILL, MICHAEL, GILLESPIE, DIRK · 1997 to 2024
$9.0M
MItochondrial Dysfunction in Cardiac Hypertrophy and FailureR01HL101235 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BERS, DONALD M, BLATTER, LOTHAR A · 2010 to 2013
$2.8M
Pathophysiological Regulation of Atrial Alternans and Atrial FibrillationR01HL132871 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI BANACH, KATHRIN, BLATTER, LOTHAR A · 2017 to 2020
$1.6M
NHLBI NIH HHS P01 HL080101NHLBI NIH HHS R01 HL057832NHLBI NIH HHS R01 HL101235NHLBI NIH HHS R01 HL132871
6 · The paper itself

Abstract

Atrial fibrillation is the most common sustained arrhythmia and its prevalence is rapidly rising with the aging of the population. Cardiac alternans, defined as cyclic beat-to-beat alternations in contraction force, action potential (AP) duration and intracellular Ca

Indexed as

Atrial FibrillationHeart AtriaMyocytes, CardiacAction PotentialsArrhythmias, CardiacHumansAction potentialAlternansArrhythmiasAtriaCalcium signaling

Identifiers

PMID28666575
PMCPMC5802406

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.