ArticlePediatric research2017
Foxd1 is an upstream regulator of the renin-angiotensin system during metanephric kidney development.
Article in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- The kidney stroma in development and disease.Nature reviews. Nephrology · 2025Review
- Tcf21 as a founder transcription factor in specifying Foxd1 cells to the juxtaglomerular cell lineage.American journal of physiology. Renal physiology · 2025Article
- The origin and role of the renal stroma.Development (Cambridge, England) · 2021Review
- Review
- Determination of the dynamic cellular transcriptional profiles during kidney development from birth to maturity in rats by single-cell RNA sequencing.Cell death discovery · 2021Article
- FOXD1 and Gal-3 Form a Positive Regulatory Loop to Regulate Lung Cancer Aggressiveness.Cancers · 2019Article
- Development of the renal vasculature.Seminars in cell & developmental biology · 2019Review
- Stromal prorenin receptor is critical for normal kidney development.American journal of physiology. Regulatory, integrative and comparative physiology · 2019Article
- knnAUC: an open-source R package for detecting nonlinear dependence between one continuous variable and one binary variable.BMC bioinformatics · 2018Article
- The multisystemic functions of FOXD1 in development and disease.Journal of molecular medicine (Berlin, Germany) · 2018Review
- Pericytes in the renal vasculature: roles in health and disease.Nature reviews. Nephrology · 2018Review
- Concepts for a therapeutic prolongation of nephrogenesis in preterm and low-birth-weight babies must correspond to structural-functional properties in the nephrogenic zone.Molecular and cellular pediatrics · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
BackgroundWe tested the hypothesis that Foxd1, a transcription factor essential for normal kidney development, is an upstream regulator of the renin-angiotensin system (RAS) during ureteric bud (UB)-branching morphogenesis.MethodsUB branching, RAS gene, and protein expression were studied in embryonic mouse kidneys. RAS mRNA expression was studied in mesenchymal MK4 cells.ResultsThe number of UB tips was reduced in Foxd1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.