ArticlePediatric research2017
The role of breast milk in the colonization of neonatal gut and skin with coagulase-negative staphylococci.
Article in Pediatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Probiotic Supplementation During the Perinatal and Infant Period: Effects on Gut Dysbiosis and Disease.Nutrients · 2020Pooled it
- A systematic review of the factors influencing microbial colonization of the preterm infant gut.Gut microbesPooled it
- Patterns of early-life microbial exposure and infection risk in hospital-born neonates in a tertiary hospital setting in Ghana.BMC microbiology · 2026Article
- IncreasedbioRxiv : the preprint server for biology · 2026Article
- Collection of human bacteria at University of Tartu, Estonia.Microbiology resource announcements · 2026Article
- Human Milk Microbiome from Polish Women Giving Birth via Vaginal Delivery-Pilot Study.Biology · 2025Article
- Effect of early directed implementation of family-integrated care measures on colonisation withBMJ paediatrics open · 2023Article
- Human Milk Microbiota Profile Affected by Prematurity in Argentinian Lactating Women.Microorganisms · 2023Article
- The Association between Infant Colic and the Multi-Omic Composition of Human Milk.Biomolecules · 2023Article
- The Role of Coagulase-Negative Staphylococci Biofilms on Late-Onset Sepsis: Current Challenges and Emerging Diagnostics and Therapies.Antibiotics (Basel, Switzerland) · 2023Review
- Dynamics of oral microbiome acquisition in healthy infants: A pilot study.Frontiers in oral health · 2023Article
- Molecular epidemiology and antibiotic resistance of staphylococci other thanFrontiers in microbiology · 2023Article
- Human Milk Oligosaccharides and Bacterial Profile Modulate Infant Body Composition during Exclusive Breastfeeding.International journal of molecular sciences · 2022Article
- Exclusively Breastfed Infant Microbiota Develops over Time and Is Associated with Human Milk Oligosaccharide Intakes.International journal of molecular sciences · 2022Article
- Human milk microbial species are associated with mild growth deficits during early infancy among Guatemalan mother-infant dyads.Frontiers in microbiomes · 2022Article
- Human milk microbial species are associated with infant head-circumference during early and late lactation in Guatemalan mother-infant dyads.Frontiers in microbiology · 2022Article
- Mother's Milk Microbiome Shaping Fecal and Skin Microbiota in Infants with Food Allergy and Atopic Dermatitis: A Pilot Analysis.Nutrients · 2021Article
- Human Milk-Based or Bovine Milk-Based Fortifiers Differentially Impact the Development of the Gut Microbiota of Preterm Infants.Frontiers in pediatrics · 2021Article
- Distinct Changes Occur in the Human Breast Milk Microbiome Between Early and Established Lactation in Breastfeeding Guatemalan Mothers.Frontiers in microbiology · 2021Article
- A systematic comparison between infant formula compositions using the Bray-Curtis Similarity Index.International journal of pediatrics & adolescent medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundWe aimed to determine the genetic relatedness between Staphylococcus epidermidis colonizing breast milk (BM) and BM-fed neonates during the first month of life.MethodsS. epidermidis was isolated from the stool and skin swabs of 20 healthy term and 49 preterm neonates hospitalized in the neonatal intensive care unit and from the BM of mothers once a week and typed by multilocus variable-number tandem-repeat analysis. Virulence-related genes were determined by PCR.ResultsThe gut (95%) and skin (100%) of term neonates were colonized with strains genetically similar to those in BM and carrying mecA and IS256 at low rate (both <6.7%). In preterm neonates, colonization with strains genetically similar to those in BM was low on the skin (34.7%) and in the gut in the first week of life (14.3%), but the prevalence of mecA (>90.6%) and IS256 (>61.7%) was high. By the fourth week, in the gut of preterm neonates the prevalence of mecA (73.8%) and IS256 (18.4%) decreased, but colonization with strains genetically similar to those in BM increased (83.7%).ConclusionDuring early life, the skin and gut of preterm neonates is colonized with S. epidermidis that is distinct from strains found in BM, but gradually the gut is enriched with strains genetically similar to those in BM, as in term neonates.
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