ArticleASAIO journal (American Society for Artificial Internal Organs : 1992)
A Membrane Lung Design Based on Circular Blood Flow Paths.
Article in ASAIO journal (American Society for Artificial Internal Organs : 1992). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Numerical Investigation of Gas Exchange Processes in Hollow-Fiber Membrane Bundles.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026Article
- Advancing extracorporeal carbon dioxide removal technology: bridging basic science and clinical practice.Medical gas research · 2025Review
- A Reduced Resistance, Concentric-Gated Artificial Membrane Lung for Pediatric End-Stage Lung Failure.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2025Article
- A Wearable Extracorporeal COBioengineering (Basel, Switzerland) · 2024Article
- Seven-day in vivo testing of a novel, low-resistance, pumpless pediatric artificial lung for long-term support.Journal of pediatric surgery · 2022Article
- A Portable Servoregulation Controller to Automate COBioengineering (Basel, Switzerland) · 2022Article
- A pumpless artificial lung without systemic anticoagulation: The Nitric Oxide Surface Anticoagulation system.Journal of pediatric surgery · 2022Article
- Advances in extracorporeal membrane oxygenator design for artificial placenta technology.Artificial organs · 2021Review
- Low-Resistance, Concentric-Gated Pediatric Artificial Lung for End-Stage Lung Failure.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2020Article
- Physiological and Technical Considerations of Extracorporeal COCritical care (London, England) · 2019Review
- Early in vivo experience with the pediatric continuous-flow total artificial heart.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
Current hollow fiber membrane lungs feature a predominantly straight blood path length across the fiber bundle, resulting in limited O2 transfer efficiency because of the diffusion boundary layer effect. Using computational fluid dynamics and optical flow visualization methods, a hollow fiber membrane lung was designed comprising unique concentric circular blood flow paths connected by gates. The prototype lung, comprising a fiber surface area of 0.28 m, has a rated flow of 2 L/min, and the oxygenation efficiency is 357 ml/min/m. The CO2 clearance of the lung is 200 ml/min at the rated blood flow. Given its high gas transfer efficiency, as well as its compact size, low priming volume, and propensity for minimal thrombogenicity, this lung design has the potential to be used in a range of acute and chronic respiratory support applications, including providing total respiratory support for infants and small children and CO2 clearance in adults.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.