ArticleNature microbiology2017
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses.
Abstract read
In one paragraph
Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 58 citations in OpenAlex.
- A comprehensive look at Respiratory Syncytial Virus (RSV): from pathogenesis to prevention.Tropical diseases, travel medicine and vaccines · 2026Review
- Respiratory syncytial viral load drives ciliated cell dedifferentiation and suppresses antiviral immunity.Science advances · 2026Article
- Structural Advances in Respiratory Syncytial Virus: Implications for Vaccine and Antiviral Development.Microorganisms · 2026Review
- Metatranscriptomics uncovers host immune and microbiome signatures specific to and shared between human metapneumovirus and respiratory syncytial virus infections in children.Virologica Sinica · 2026Article
- AI-Assisted Computed Structure Models for Pre-Ubiquitylation Complexes Assembled by Respiratory Syncytial Viral Suppressors of Cellular Interferon Response.International journal of molecular sciences · 2026Article
- Article
- Respiratory Syncytial Virus Nonstructural Protein 1 Inhibits Production of Cytokines and Chemokines by Differentiated Primary Nasal Epithelial Cells Cultured at Air-Liquid Interface.Journal of innate immunity · 2026Article
- Epidemiological characteristics and whole-genome analysis of respiratory syncytial virus in Jining city from February 2023 to December 2024.Frontiers in microbiology · 2026Article
- When defense backfires: inflammatory determinants of RSV-induced disease severity.Future virology · 2026Article
- Next-generation single-cycle respiratory syncytial virus vaccines with increased type I interferon induction yield robust systemic and mucosal responses in mice.Frontiers in immunology · 2026Article
- Analysis of DNA methyltransferase 3 alpha expression during respiratory syncytial virus strain A infection.Scientific reports · 2025Article
- Review
- A dual interaction between RSV NS1 and MED25 ACID domain reshapes antiviral responses.PLoS pathogens · 2025Article
- Advances in development of antiviral strategies against respiratory syncytial virus.Acta pharmaceutica Sinica. B · 2025Review
- Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25.Nature communications · 2025Article
- Review
- Introduction to Respiratory Syncytial Virus.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Expression and Purification of Recombinant Respiratory Syncytial Virus Proteins.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Pathogenicity and virulence of human respiratory syncytial virus: Multifunctional nonstructural proteins NS1 and NS2.Virulence · 2024Review
- Genomic characteristics of human respiratory syncytial virus from children in China during 2017-2020.Archives of virology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 2 countries.
Srirupa ChatterjeeDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Priya LuthraCenter for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia 30303, USA.
Ekaterina EsaulovaDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.ORCID http://orcid.org/0000-0001-9806-662X
Eugene AgapovDepartment of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Benjamin C YenDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Dominika M BorekDepartments of Biophysics and Biochemistry, University of Texas Southwestern Medical Center, Texas 75390, USA.ORCID http://orcid.org/0000-0002-4321-6253
Megan R EdwardsDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Anuradha MittalDepartment of Biomedical Engineering, Center for Biological Systems Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, USA.
David S JordanDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Parameshwar RamananDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Martin L MooreDivision of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Rohit V PappuDepartment of Biomedical Engineering, Center for Biological Systems Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, USA.ORCID http://orcid.org/0000-0003-2568-1378
Michael J HoltzmanDepartment of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Maxim N ArtyomovDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Christopher F BaslerCenter for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia 30303, USA.
Gaya K AmarasingheDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.ORCID http://orcid.org/0000-0002-0418-9707
Daisy W LeungDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.ORCID http://orcid.org/0000-0002-7189-9557
Washington University in St. Louis · USGeorgia State University · USEmory University · USIcahn School of Medicine at Mount Sinai · USITMO University · RUThe University of Texas Southwestern Medical Center · US
Funding
Viral and Host Determinants of Infant and Childhood Allergy and AsthmaU19AI095227 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Dawn C Newcomb · 2011 to 2026
$34.9MVirology BSL4 CoreP01AI120943 · NIAID · WASHINGTON UNIVERSITY · PI Gaya K. Amarasinghe · 2016 to 2026
$30.2MTissue and Cell Processing CoreU19AI070489 · NIAID · WASHINGTON UNIVERSITY · PI HOLTZMAN, MICHAEL J · 2006 to 2016
$17.9MTherapeutics Targeting Filoviral interferon-antagonist and replication functionsU19AI109664 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BASLER, CHRISTOPHER F · 2014 to 2018
$15.8MTRAINING IN THE IMMUNOBIOLOGY AND MOLECULAR CELL BIOLOGY OF CANCERT32CA009547 · NCI · WASHINGTON UNIVERSITY · PI ROBERT DAVID SCHREIBER · 1986 to 2026
$12.1MMolecular mechanisms of immune dysregulation by filoviral interferon U19AI109945 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BASLER, CHRISTOPHER F · 2014 to 2018
$9.5MPreclinical Development of an Anti-Mucus DrugUH3HL123429 · NHLBI · WASHINGTON UNIVERSITY · PI HOLTZMAN, MICHAEL J · 2016 to 2018
$4.7MSmall Molecule Inhibitors of Ebola Virus Polymerase FunctionR01AI125453 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BASLER, CHRISTOPHER F · 2017 to 2021
$4.3MPARP9-DTX3L Control Of Viral Infection and Airway DiseaseR01AI130591 · NIAID · WASHINGTON UNIVERSITY · PI HOLTZMAN, MICHAEL J · 2017 to 2021
$3.0MMulti-platform High Throughput Screens for Filoviral Replication InhibitorsR01AI123926 · NIAID · WASHINGTON UNIVERSITY · PI AMARASINGHE, GAYA K. · 2016 to 2018
$2.1MSTRUCTURAL BASIS FOR IMMUNE EVASION BY RSV NON-STRUCTURAL PROTEINSR01AI107056 · NIAID · WASHINGTON UNIVERSITY · PI LEUNG, DAISY W · 2013 to 2017
$1.9MRole of the Respiratory Syncytial Virus Fusion Protein in Airway Mucus InductionR01AI087798 · NIAID · EMORY UNIVERSITY · PI MOORE, MARTIN LAWRENCE · 2010 to 2014
$1.9MNCI NIH HHS T32 CA009547NHLBI NIH HHS UH3 HL123429NIAID NIH HHS P01 AI120943NIAID NIH HHS R01 AI087798NIAID NIH HHS R01 AI107056NIAID NIH HHS R01 AI111605NIAID NIH HHS R01 AI114654NIAID NIH HHS R01 AI123926NIAID NIH HHS R01 AI125453NIAID NIH HHS R01 AI130591NIAID NIH HHS U19 AI070489NIAID NIH HHS U19 AI095227NIAID NIH HHS U19 AI109664NIAID NIH HHS U19 AI109945
Abstract
Human respiratory syncytial virus (hRSV) is a major cause of morbidity and mortality in the paediatric, elderly and immune-compromised populations
Indexed as
Host-Pathogen InteractionsA549 CellsAnimalsChlorocebus aethiopsDendritic CellsHumansInterferon Type IMutationProtein DomainsProtein FoldingProtein Structure, SecondaryRespiratory Syncytial Virus, HumanTranscriptomeVero CellsViral Matrix ProteinsViral Nonstructural ProteinsInterferon Type IViral Matrix ProteinsViral Nonstructural Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.