Evidence map›Paper›PMID 28665005›Full record

ArticleEuropean journal of immunology2017

Toll like Receptor 2 engagement on CD4

Ahmad Faisal Karim, Scott M Reba, Qing Li, W Henry Boom, Roxana E Rojas

Open access · bronzeAbstract read
In one paragraph

Article in European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

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  20. Interleukin-9 in Immunopathology ofFrontiers in cellular and infection microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ahmad Faisal KarimDivision of Infectious Diseases, Department of Medicine, Case Western Reserve University & University Hospitals, Cleveland, OH, USA.ORCID 0000-0001-7714-297X
Scott M RebaDivision of Infectious Diseases, Department of Medicine, Case Western Reserve University & University Hospitals, Cleveland, OH, USA.
Qing LiDivision of Infectious Diseases, Department of Medicine, Case Western Reserve University & University Hospitals, Cleveland, OH, USA.
W Henry BoomDivision of Infectious Diseases, Department of Medicine, Case Western Reserve University & University Hospitals, Cleveland, OH, USA.
Roxana E RojasDivision of Infectious Diseases, Department of Medicine, Case Western Reserve University & University Hospitals, Cleveland, OH, USA.
University Hospitals of Cleveland · USUniformed Services University of the Health Sciences · US

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI MARK R CHANCE · 1987 to 2026
$142.3M
WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Sharon L. Hillier, JONATHAN KARN · 1994 to 2026
$50.0M
HETEROGENEITY OF TCELLS IN M TUBERCULOSIS INFECTIONR01AI027243 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BOOM, W. HENRY · 1989 to 2016
$5.5M
Role of TLR2 engagement on CD4+ T cells in immunity to M. tuberculosisR21AI099494 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROJAS, ROXANA E. · 2012 to 2013
$432k
NCI NIH HHS P30 CA043703NIAID NIH HHS N01 AI070022NIAID NIH HHS P30 AI036219NIAID NIH HHS R01 AI027243NIAID NIH HHS R21 AI099494
6 · The paper itself

Abstract

We have recently demonstrated that mycobacterial ligands engage Toll like receptor 2 (TLR2) on CD4

Indexed as

AcyltransferasesAnimalsAntigens, BacterialBacterial ProteinsCD4-Positive T-LymphocytesCell DifferentiationCells, CulturedCytokinesHumansInterferon-gammaInterleukin-9Lymphocyte ActivationMiceMice, Inbred C57BLProto-Oncogene ProteinsProto-Oncogene Protein Spi-1Acyltransferasesantigen 85B, Mycobacterium tuberculosisAntigens, BacterialBacterial ProteinsCytokinesInterferon-gammaInterleukin-9Proto-Oncogene ProteinsProto-Oncogene Protein Spi-1Receptors, Antigen, T-CellToll-Like Receptor 2Trans-ActivatorsBATFCD4+IL9PU.1T cellsTH9 T cellsToll like receptor 2

Identifiers

PMID28665005
PMCPMC5606324
OpenAlexW2727988820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.