Evidence map›Paper›PMID 28664640›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Diazirines as Potential Molecular Imaging Tags: Probing the Requirements for Efficient and Long-Lived SABRE-Induced Hyperpolarization.

Kun Shen, Angus W J Logan, Johannes F P Colell, Junu Bae, Gerardo X Ortiz, Thomas Theis, Warren S Warren, Steven J Malcolmson, Qiu Wang

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 66 citations in OpenAlex.

  1. Hyperpolarization of PyridineAngewandte Chemie (International ed. in English) · 2026
    Article
  2. HyperpolarizedACS sensors · 2026
    Article
  3. Review
  4. The Versatility of Diazirines: Properties, Synthetic and Modern Applications.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Hyperpolarization of common antifungal agents with SABRE.Magnetic resonance in chemistry : MRC · 2021
    Article
  15. Chemical science · 2021
    Article
  16. Article
  17. Review
  18. Hyperpolarization of cis-Chemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
  19. Synthetic Approaches forChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  20. Synthesis andChemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kun ShenDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.
Angus W J LoganDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.ORCID 0000-0003-3985-9835
Johannes F P ColellDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.ORCID 0000-0001-9020-344X
Junu BaeDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.
Gerardo X OrtizDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.
Thomas TheisDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.ORCID 0000-0001-6779-9978
Warren S WarrenDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.
Steven J MalcolmsonDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.ORCID 0000-0003-3229-0949
Qiu WangDepartment of Chemistry, Duke University, French Family Science Center, 124 Science Drive, Durham, NC, 27708, USA.ORCID 0000-0002-6803-9556
Duke University · US

Funding

Probing Hyperpolarized 15N2-diazirine as A Universal Molecular Tag in MRIR21EB024824 · NIBIB · DUKE UNIVERSITY · PI WANG, QIU · 2018 to 2019
$427k
NIBIB NIH HHS R21 EB024824
6 · The paper itself

Abstract

Diazirines are an attractive class of potential molecular tags for magnetic resonance imaging owing to their biocompatibility and ease of incorporation into a large variety of molecules. As recently reported,

Indexed as

diazirinehyperpolarizationimaging agentsiridiumstructure-activity relationships

Identifiers

PMID28664640
PMCPMC9310518
OpenAlexW2729707084

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.