Evidence map›Paper›PMID 28664546›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2017

Diet-independent relevance of serum uric acid for blood pressure in a representative population sample.

Danika Krupp, Jonas Esche, Gert Bm Mensink, Hannelore K Neuhauser, Thomas Remer

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Effects and Mechanisms of Dapagliflozin Treatment on Ambulatory Blood Pressure in Diabetic Patients with Hypertension.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Relationship between serum uric acid and blood pressure by adjusting dietary factors.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Danika KruppDONALD Study Dortmund, Department of Nutrition and Food Sciences (IEL), Nutritional Epidemiology, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0001-7272-4807
Jonas EscheDONALD Study Dortmund, Department of Nutrition and Food Sciences (IEL), Nutritional Epidemiology, University of Bonn, Bonn, Germany.
Gert Bm MensinkDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Hannelore K NeuhauserDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Thomas RemerDONALD Study Dortmund, Department of Nutrition and Food Sciences (IEL), Nutritional Epidemiology, University of Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A direct relationship between serum uric acid and blood pressure (BP) has been reported, but the possible confounding impact of diet on this association is unclear. The authors performed a cross-sectional analysis in the representative German Health Interview and Examination Survey for Adults (n=6788, aged 18-79 years). In adjusted regression models considering dietary factors, each 1-mg/dL higher uric acid value was associated with a 1.10-mm Hg (P=.0002) and a 0.60-mm Hg (P=.04) higher systolic BP among participants younger than 50 years and participants 50 years and older, respectively. For diastolic BP, uric acid was a significant predictor (β=0.71 mm Hg, P=.0001) among participants younger than 50 years and for participants 50 years and older without antihypertensive treatment. Adjusted odds ratios of hypertension for participants with hyperuricemia were broadly similar in younger (odds ratio, 1.71; P=.02) and older (odds ratio, 1.81; P=.0003) participants. Uric acid is a significant predictor of systolic BP and hypertension prevalence in the general adult population in Germany independently of several known dietary BP influences.

Indexed as

AdolescentAdultAgedBlood PressureCross-Sectional StudiesDietDose-Response Relationship, DrugFemaleGermanyHumansHypertensionHyperuricemiaMaleMiddle AgedPrevalenceRisk FactorsUric AciddietGermanyhypertensionuric acid

Identifiers

PMID28664546
PMCPMC8031238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.