Evidence map›Paper›PMID 28664188›Full record

ArticleMacrophage2017

Mammary epithelial polarity and macrophage infiltration.

Ren Xu

Abstract read
In one paragraph

Article in Macrophage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ren XuMarkey Cancer Center, University of Kentucky, Lexington, KY 40536, USA.

Funding

Roles of Hsp47 in Breast Cancer ProgressionR01CA207772 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI XU, REN · 2017 to 2025
$3.1M
Systemic delivery of miR-29 for basal-like breast cancer treatmentR21CA209045 · NCI · UNIVERSITY OF KENTUCKY · PI SHU, DAN, XU, REN · 2016 to 2017
$375k
American Heart Association-American Stroke Association 12SDG8600000NCI NIH HHS R01 CA207772NCI NIH HHS R21 CA209045
6 · The paper itself

Abstract

Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epithelial cells and monocytes, a recent study reveals a link between disruption of epithelial polarity and monocytes infiltration.

Indexed as

cancer progressioncell polarityInflammationmacrophage infiltrationreactive oxygen species

Identifiers

PMID28664188
PMCPMC5485912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.