ArticleGenomics data2017
Oviductal transcriptional profiling of a bovine fertility model by next-generation sequencing.
Article in Genomics data, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Spatiotemporal transcriptional dynamics of the cycling mouse oviduct.Developmental biology · 2021Article
- Steroidal Regulation of Oviductal microRNAs Is Associated with microRNA-Processing in Beef Cows.International journal of molecular sciences · 2021Article
- Changes in Oviductal Cells and Small Extracellular Vesicles miRNAs in Pregnant Cows.Frontiers in veterinary science · 2021Article
- Relative effects of location relative to the corpus luteum and lactation on the transcriptome of the bovine oviduct epithelium.BMC genomics · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In cattle, the oviduct plays a fundamental role in the reproductive process. Oviductal functions are controlled by the ovarian sex steroids: estradiol and progesterone. Here, we tested the hypothesis that the exposure to contrasting sex steroid milieus differentially impacts the oviductal transcriptional profile. We manipulated growth of the pre-ovulatory follicle to obtain cows that ovulated a larger (LF group) or a smaller (SF group) follicle. The LF group presented greater proestrus/estrus concentrations of estradiol and metaestrus concentrations of progesterone (Gonella-Diaza et al. 2015 [1], Mesquita et al. 2014 [2]). Also, the LF group was associated with greater fertility in timed-artificial insemination programs (Pugliesi et al. 2016 [3]). Cows were slaughtered on day 4 of the estrous cycle and total RNA was extracted from ampulla and isthmus fragments and analyzed by RNAseq. The resulting reads were mapped to the bovine genome (
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Registered trials
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