Evidence map›Paper›PMID 28664093›Full record

ReviewIntegrative medicine research2014

Recent advances in mitochondrial turnover during chronic muscle disuse.

Liam D Tryon, Anna Vainshtein, Jonathan M Memme, Matthew J Crilly, David A Hood

Abstract readReview
In one paragraph

Review in Integrative medicine research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Antioxidants (Basel, Switzerland) · 2021
    Article
  7. Mitochondrial Bioenergetics and Turnover during Chronic Muscle Disuse.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  14. Article
  15. Combination of Coenzyme QOxidative medicine and cellular longevity · 2018
    Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liam D TryonMuscle Health Research Centre, School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada.
Anna VainshteinMuscle Health Research Centre, School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada.
Jonathan M MemmeMuscle Health Research Centre, School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada.
Matthew J CrillyMuscle Health Research Centre, School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada.
David A HoodMuscle Health Research Centre, School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic muscle disuse, such as that resulting from immobilization, denervation, or prolonged physical inactivity, produces atrophy and a loss of mitochondria, yet the molecular relationship between these events is not fully understood. In this review we attempt to identify the key regulatory steps mediating the loss of muscle mass and the decline in mitochondrial content and function. An understanding of common intracellular signaling pathways may provide much-needed insight into the possible therapeutic targets for treatments that will maintain aerobic energy metabolism and preserve muscle mass during disuse conditions.

Indexed as

denervationmitochondrial biogenesismitophagyprotein degradationskeletal muscle

Identifiers

PMID28664093
PMCPMC5481769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.