Evidence map›Paper›PMID 28664031›Full record

ArticleNeuroImage. Clinical2017

Large-scale structural alteration of brain in epileptic children with

Yun-Jeong Lee, Mi-Sun Yum, Min-Jee Kim, Woo-Hyun Shim, Hee Mang Yoon, Il Han Yoo, Jiwon Lee, Byung Chan Lim, Ki Joong Kim, Tae-Sung Ko

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

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  6. Use of Zebrafish Models to Boost Research in Rare Genetic Diseases.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Yun-Jeong LeeDepartment of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Mi-Sun YumDepartment of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Min-Jee KimDepartment of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Woo-Hyun ShimDepartment of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Hee Mang YoonDepartment of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Il Han YooDepartment of Pediatrics, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Republic of Korea.
Jiwon LeeDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Byung Chan LimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Ki Joong KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea. Electronic address: pednr@plaza.snu.ac.kr.
Tae-Sung KoDepartment of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address: tsko@amc.seoul.kr.
University of Ulsan · KRAsan Medical Center · KRSeoul National University Children's Hospital · KRSamsung Medical Center · KRThe Catholic University of Korea St. Vincent's Hospital · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMutations in

methodsWe obtained cortical morphology (thickness, and surface area) and brain volume (global, subcortical, and regional) measurements using FreeSurfer (version 5.3.0, https://surfer.nmr.mgh.harvard.edu) and compared measurements of children with epilepsy and

resultsCompared to the healthy control group, children with epilepsy and SIGNIFICANCE: This study showed large-scale developmental brain changes in patients with epilepsy and

Indexed as

ChildChild, PreschoolEpilepsyEpileptic SyndromesFemaleHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMutationNAV1.1 Voltage-Gated Sodium ChannelNAV1.1 Voltage-Gated Sodium ChannelSCN1A protein, humanBrain volumeChildrenCSF, cerebrospinal fluidEpilepsyGEFS +,  genetic epilepsy with febrile seizures plusGM, gray matterMagnetic resonance imagingMRI, magnetic resonance imagingSCN1ASMEI, severe myoclonic epilepsy of infancySurface areaTIV, total intracranial volumeWM, white matter

Identifiers

PMID28664031
PMCPMC5479971
OpenAlexW2623192551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.