ArticleBiomedical optics express2017
Use of a handheld terahertz pulsed imaging device to differentiate benign and malignant breast tissue.
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 83 citations in OpenAlex.
- Optimized Calibration of Terahertz Polarimetric Imaging Systems With Imperfect Polarizers for Accurate Jones-Matrix Mapping.Research square · 2026Article
- Terahertz spectral imaging for early assessment of frostbite injuries using the double Debye model and supervised machine learning.Biomedical optics express · 2026Article
- Review
- Rapid diagnosis of TERT promoter mutation using Terahertz absorption spectroscopy in glioblastoma.Scientific reports · 2025Article
- A handheld polarimetric imaging device and calibration technique for accurate mapping of terahertz Stokes vectors.Scientific reports · 2024Article
- Biomedical application of terahertz imaging technology: a narrative review.Quantitative imaging in medicine and surgery · 2023Review
- Triage ofBiomedical optics express · 2023Article
- Terahertz PHASR Scanner with 2 kHz, 100 picosecond Time-Domain Trace Acquisition Rate and an Extended Field-of-View Based on a Heliostat Design.IEEE transactions on terahertz science and technology · 2022Article
- Accurate and early prediction of the wound healing outcome of burn injuries using the wavelet Shannon entropy of terahertz time-domain waveforms.Journal of biomedical optics · 2022Article
- In Vivo Assessment and Monitoring of Burn Wounds Using a Handheld Terahertz Hyperspectral Scanner.Advanced photonics research · 2022Article
- Deep neural network classification of in vivo burn injuries with different etiologies using terahertz time-domain spectral imaging.Biomedical optics express · 2022Article
- Supervised machine learning for automatic classification of in vivo scald and contact burn injuries using the terahertz Portable Handheld Spectral Reflection (PHASR) Scanner.Scientific reports · 2022Article
- Terahertz Imaging for Breast Cancer Detection.Sensors (Basel, Switzerland) · 2021Review
- Non-contact terahertz spectroscopic measurement of the intraocular pressure through corneal hydration mapping.Biomedical optics express · 2021Article
- A Review of Feasible Applications of THz Waves in Medical Diagnostics and Treatments.Journal of lasers in medical sciences · 2021Review
- Terahertz time-domain spectral imaging using telecentric beam steering and an f-θscanning lens: distortion compensation and determination of resolution limits.Optics express · 2020Article
- Terahertz Imaging and Spectroscopy in Cancer Diagnostics: A Technical Review.BME frontiers · 2020Review
- Terahertz Portable Handheld Spectral Reflection (PHASR) Scanner.IEEE access : practical innovations, open solutions · 2020Article
- Terahertz tomographic imaging of freshly excised human breast tissues.Journal of medical imaging (Bellingham, Wash.) · 2019Article
- Cancer detection in excised breast tumors using terahertz imaging and spectroscopy.Biomedical spectroscopy and imaging · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since nearly 20% of breast-conserving surgeries (BCS) require re-operation, there is a clear need for developing new techniques to more accurately assess tumor resection margins intraoperatively. This study evaluates the diagnostic accuracy of a handheld terahertz pulsed imaging (TPI) system to discriminate benign from malignant breast tissue ex vivo. Forty six freshly excised breast cancer samples were scanned with a TPI handheld probe system, and histology was obtained for comparison. The image pixels on TPI were classified using (1) parameters in combination with support vector machine (SVM) and (2) Gaussian wavelet deconvolution in combination with Bayesian classification. The results were an accuracy, sensitivity, specificity of 75%, 86%, 66% for method 1, and 69%, 87%, 54% for method 2 respectively. This demonstrates the probe can discriminate invasive breast cancer from benign breast tissue with an encouraging degree of accuracy, warranting further study.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.