Evidence map›Paper›PMID 28663910›Full record

ArticleBiomedical optics express2017

Raman active components of skin cancer.

Xu Feng, Austin J Moy, Hieu T M Nguyen, Jason Zhang, Matthew C Fox, Katherine R Sebastian, Jason S Reichenberg, Mia K Markey, James W Tunnell

Registry-linked trialAbstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04040673 (Evaluation of the Role of Vibrational Spectroscopy in the Diagnosis of Premalignant and Malignant Disease of the Thyroid RAFTER), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04040673 unknown statusnot on this mapstarted 2024, after this paper: background citation

Evaluation of the Role of Vibrational Spectroscopy in the Diagnosis of Premalignant and Malignant Disease of the Thyroid RAFTER (RAman For Thyroid cancER)

TypeobservationalSponsorGloucestershire Hospitals NHS Foundation TrustRan2024 to 2025Enrolled40ConditionsThyroid Diseases, Thyroid CancerArmsthyroid lobectomy, Raman spectroscopy probe measurement
3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Multi-Wavelength Raman Differentiation of Malignant Skin Neoplasms.International journal of molecular sciences · 2024
    Article
  7. Article
  8. Direct observation of the effects of chemical fixation in MNT-1 cells: A SE-ADM and Raman study.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xu FengDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton Street C0800, Austin, TX 78712, USA.
Austin J MoyDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton Street C0800, Austin, TX 78712, USA.
Hieu T M NguyenDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton Street C0800, Austin, TX 78712, USA.
Jason ZhangDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton Street C0800, Austin, TX 78712, USA.
Matthew C FoxMedicine, Dell Medical School, The University of Texas at Austin, 1400 N IH-35 Suite C2-470, Austin, TX 78701, USA.
Katherine R SebastianMedicine, Dell Medical School, The University of Texas at Austin, 1400 N IH-35 Suite C2-470, Austin, TX 78701, USA.
Jason S ReichenbergMedicine, Dell Medical School, The University of Texas at Austin, 1400 N IH-35 Suite C2-470, Austin, TX 78701, USA.
Mia K MarkeyDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton Street C0800, Austin, TX 78712, USA.
James W TunnellDepartment of Biomedical Engineering, The University of Texas at Austin, 107 W. Dean Keeton Street C0800, Austin, TX 78712, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Raman spectroscopy (RS) has shown great potential in noninvasive cancer screening. Statistically based algorithms, such as principal component analysis, are commonly employed to provide tissue classification; however, they are difficult to relate to the chemical and morphological basis of the spectroscopic features and underlying disease. As a result, we propose the first Raman biophysical model applied to

Indexed as

(170.1610) Clinical applications(170.1790) Confocal microscopy(170.3880) Medical and biological imaging(170.6510) Spectroscopy, tissue diagnostics(300.6450) Spectroscopy, Raman

Identifiers

PMID28663910
PMCPMC5480433

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.