Evidence map›Paper›PMID 28663902›Full record

ArticleBiomedical optics express2017

Automatic segmentation of nine retinal layer boundaries in OCT images of non-exudative AMD patients using deep learning and graph search.

Leyuan Fang, David Cunefare, Chong Wang, Robyn H Guymer, Shutao Li, Sina Farsiu

Abstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 196 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
196citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

196 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. A deep learning model for automated identification of age-related macular degeneration atrophy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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  15. Quantitative assessment ofBiomedical optics express · 2025
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136 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leyuan FangDepartments of Biomedical Engineering Duke University, Durham, NC 27708, USA.
David CunefareDepartments of Biomedical Engineering Duke University, Durham, NC 27708, USA.
Chong WangCollege of Electrical and Information Engineering, Hunan University, Changsha 410082, China.
Robyn H GuymerCentre for Eye Research Australia University of Melbourne, Department of Surgery, Royal Victorian Eye and Ear Hospital, Victoria 3002, Australia.
Shutao LiCollege of Electrical and Information Engineering, Hunan University, Changsha 410082, China.
Sina FarsiuDepartments of Biomedical Engineering Duke University, Durham, NC 27708, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a novel framework combining convolutional neural networks (CNN) and graph search methods (termed as CNN-GS) for the automatic segmentation of nine layer boundaries on retinal optical coherence tomography (OCT) images. CNN-GS first utilizes a CNN to extract features of specific retinal layer boundaries and train a corresponding classifier to delineate a pilot estimate of the eight layers. Next, a graph search method uses the probability maps created from the CNN to find the final boundaries. We validated our proposed method on 60 volumes (2915 B-scans) from 20 human eyes with non-exudative age-related macular degeneration (AMD), which attested to effectiveness of our proposed technique.

Indexed as

(100.0100) Image processing(100.2960) Image analysis(110.4500) Optical coherence tomography

Identifiers

PMID28663902
PMCPMC5480509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.