ReviewBiomedical optics express2017
Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging [Invited].
Review in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
113 citing papers in PubMed.
- Automated Segmentation of Retinal Pigment Epithelium Layers in High-Resolution OCT.Ophthalmology science · 2026Article
- Variable Temporal Interval OCTA Velocimetry Enables Wide-Range Hemodynamic Mapping in Hyperoxia Models.Investigative ophthalmology & visual science · 2026Article
- Histology correlated adaptive optics polarisation sensitive optical coherence tomography.Biomedical optics express · 2026Article
- Robust wavefront correction using AdamW-enhanced SPGD for computational adaptive optics in optical coherence tomography.Biomedical optics express · 2026Article
- Coefficient-metric gradient-based digital wavefront correction for full-field swept-source optical coherence tomography.Biomedical optics express · 2026Article
- Retinal structure and function recovery over five years in Vogt-Koyanagi-Harada disease using adaptive optics and microperimetry.Scientific reports · 2026Article
- Computational aberration correction enables full-thickness retinal imaging with adaptive optics optical coherence tomography.Biocybernetics and biomedical engineering · 2026Article
- Clinical and economic impacts of optical coherence tomography prior to cataract surgery in a low-to-middle-income country.Frontiers in ophthalmology · 2026Article
- Integrated fixation and stimulus channel for adaptive optics ophthalmoscopy.Biomedical optics express · 2025Article
- Brain and retina in Alzheimer's disease: Pathological intersections and estimates from imaging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Deep reinforcement learning for automatic defocus correction using OCT image intensity.Biomedical optics express · 2025Article
- Longitudinal Structural and Microvascular Imaging of Mouse Retina After Optic Nerve Crush Using Temporal Speckle-Averaging Visible Light OCT.Investigative ophthalmology & visual science · 2025Article
- Tailored-Reflectivity Microstructures for Measuring Signal Sensitivity of Optical Coherence Tomography Medical Imaging Systems.Advanced materials technologies · 2025Article
- Visual motion thresholds mapped to midget and parasol ganglion cell topography in the human retina.Scientific reports · 2025Article
- How early can we detect diabetic retinopathy? A narrative review of imaging tools for structural assessment of the retina.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Light and metabolism: label-free optical imaging of metabolic activities in biological systems [Invited].Biomedical optics express · 2025Review
- Dynamics of color vision recovery in Vogt-Koyanagi-Harada disease: a longitudinal study using cone contrast test and adaptive optics imaging.Journal of ophthalmic inflammation and infection · 2025Article
- Retinal vessel density and cognitive function in healthy older adults.Experimental brain research · 2025Article
- Optical Imaging of Cilia in the Head and Neck.Journal of clinical medicine · 2025Review
- Image Quality in Adaptive Optics Optical Coherence Tomography of Diabetic Patients.Diagnostics (Basel, Switzerland) · 2025Article
53 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In vivo imaging of the human retina with a resolution that allows visualization of cellular structures has proven to be essential to broaden our knowledge about the physiology of this precious and very complex neural tissue that enables the first steps in vision. Many pathologic changes originate from functional and structural alterations on a cellular scale, long before any degradation in vision can be noted. Therefore, it is important to investigate these tissues with a sufficient level of detail in order to better understand associated disease development or the effects of therapeutic intervention. Optical retinal imaging modalities rely on the optical elements of the eye itself (mainly the cornea and lens) to produce retinal images and are therefore affected by the specific arrangement of these elements and possible imperfections in curvature. Thus, aberrations are introduced to the imaging light and image quality is degraded. To compensate for these aberrations, adaptive optics (AO), a technology initially developed in astronomy, has been utilized. However, the axial sectioning provided by retinal AO-based fundus cameras and scanning laser ophthalmoscope instruments is limited to tens of micrometers because of the rather small available numerical aperture of the eye. To overcome this limitation and thus achieve much higher axial sectioning in the order of 2-5µm, AO has been combined with optical coherence tomography (OCT) into AO-OCT. This enabled for the first time in vivo volumetric retinal imaging with high isotropic resolution. This article summarizes the technical aspects of AO-OCT and provides an overview on its various implementations and some of its clinical applications. In addition, latest developments in the field, such as computational AO-OCT and wavefront sensor less AO-OCT, are covered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.