Evidence map›Paper›PMID 28663847›Full record

ArticleBiomedical optics express2017

Development of a multimodal foveated endomicroscope for the detection of oral cancer.

Adam Shadfan, Hawraa Darwiche, Jesus Blanco, Ann Gillenwater, Rebecca Richards-Kortum, Tomasz S Tkaczyk

Abstract read
In one paragraph

Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Hyperspectral Imaging and the Retina: Worth the Wave?Translational vision science & technology · 2020
    Pooled it
  2. Article
  3. Surgical spectral imaging.Medical image analysis · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adam ShadfanRice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005, USA.
Hawraa DarwicheDepartment of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.
Jesus BlancoDepartment of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.
Ann GillenwaterDepartment of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.
Rebecca Richards-KortumRice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005, USA.
Tomasz S TkaczykRice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005, USA.

Funding

Optical Systems for In Vivo Molecular Imaging of CancerR01CA103830 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI RICHARDS-KORTUM, REBECCA R. · 2004 to 2015
$12.4M
Miniature Foveated Endoscope for Early Cancer DiagnosticsR21EB015022 · NIBIB · RICE UNIVERSITY · PI TKACZYK, TOMASZ S · 2012 to 2013
$425k
NCI NIH HHS R01 CA103830NIBIB NIH HHS R21 EB015022
6 · The paper itself

Abstract

A multimodal endomicroscope was developed for cancer detection that combines hyperspectral and confocal imaging through a single foveated objective and a vibrating optical fiber bundle. Standard clinical examination has a limited ability to identify early stage oral cancer. Optical detection methods are typically restricted by either achievable resolution or a small field-of-view. By combining high resolution and widefield spectral imaging into a single probe, a device was developed that provides spectral and spatial information over a 5 mm field to locate suspicious lesions that can then be inspected in high resolution mode. The device was evaluated on

Indexed as

(170.1790) Confocal microscopy(170.2150) Endoscopic imaging(170.3880) Medical and biological imaging(170.3890) Medical optics instrumentation(350.3950) Micro-optics

Identifiers

PMID28663847
PMCPMC5480562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.