ArticleBiomedical optics express2017
Optically sectioned wide-field fluorescence lifetime imaging microscopy enabled by structured illumination.
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Fluorescence properties of collagen types I-V: a comprehensive study of spectral and lifetime characteristics.Journal of biomedical optics · 2026Article
- Advances in fluorescence-based point-of-care diagnostics: probes, nanostructures and integrated systems.Journal of materials chemistry. C · 2026Review
- Fluorescence Properties of Collagen Types I-V: A Comprehensive Study of Spectral and Lifetime Characteristics.bioRxiv : the preprint server for biology · 2026Article
- Isolating subsurface fluorescence in macroscopic lifetime imaging via high-spatial-frequency structured illumination.JPhys photonics · 2025Article
- Identification of colorectal malignancies enabled by phasor-based autofluorescence lifetime macroimaging and ensemble learning.Biophotonics discovery · 2025Article
- Detection and characterization of colorectal cancer by autofluorescence lifetime imaging on surgical specimens.Scientific reports · 2024Article
- Dual excitation spectral autofluorescence lifetime and reflectance imaging for fast macroscopic characterization of tissues.Biomedical optics express · 2024Article
- A time-correlated single photon counting SPAD array camera with a bespoke data-processing algorithm for lightsheet fluorescence lifetime imaging (FLIM) and FLIM videos.Scientific reports · 2024Article
- Answering some questions about structured illumination microscopy.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022Article
- Bioimaging of Dissolvable Microneedle Arrays: Challenges and Opportunities.Research (Washington, D.C.) · 2022Review
- Enhanced detection of oral dysplasia by structured illumination fluorescence lifetime imaging microscopy.Scientific reports · 2021Article
- Clinical label-free biochemical and metabolic fluorescence lifetime endoscopic imaging of precancerous and cancerous oral lesions.Oral oncology · 2020Article
- Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications.Journal of biomedical optics · 2020Review
- Real-time visualization of two-photon fluorescence lifetime imaging microscopy using a wavelength-tunable femtosecond pulsed laser.Biomedical optics express · 2018Article
- Accurate Rapid Lifetime Determination on Time-Gated FLIM Microscopy with Optical Sectioning.Journal of healthcare engineering · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
In this paper, we demonstrate the ability of structured illumination microscopy to enhance the ability of fluorescence lifetime imaging to resolve fluorescence lifetimes in relatively thick samples that possess distinct but spectrally overlapping fluorescent layers. Structured illumination fluorescent lifetime imaging microscopy (SI-FLIM) is shown to be able to accurately reconstruct lifetime values in homogenous fluorophore samples (POPOP, NADH, and FAD) as well as accurately measure fluorescent lifetime in two layer models that are layered with NADH/FAD over POPOP, where NADH/FAD and POPOP have spectral overlap. Finally, the ability of SI-FLIM was demonstrated in a hamster cheek pouch
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Registered trials
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