ArticleBiomedical optics express2017
Heart structural remodeling in a mouse model of Duchenne cardiomyopathy revealed using optical polarization tractography [Invited].
Article in Biomedical optics express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Design considerations for optogenetic applications of soft micro-LED-based device systems across diverse nervous systems.Bioactive materials · 2025Review
- Conventional Method of Cardiac Ischemia/Reperfusion Injury in Mice.Methods in molecular biology (Clifton, N.J.) · 2024Article
- High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging.Biomedical optics express · 2020Article
- Development of a polarized hyperspectral microscope for cardiac fiber orientation imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- High-resolution 3D tractography of fibrous tissue based on polarization-sensitive optical coherence tomography.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Imaging of subendocardial adipose tissue and fiber orientation distributions in the human left atrium using optical coherence tomography.Journal of cardiovascular electrophysiology · 2019Article
- Characterization of the human myocardium by optical coherence tomography.Journal of biophotonics · 2019Article
- Simultaneous tractography and elastography imaging of the zone-specific structural and mechanical responses in articular cartilage under compressive loading.Biomedical optics express · 2019Article
- Optical coherence tomography imaging of cardiac substrates.Quantitative imaging in medicine and surgery · 2019Review
- "Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic.Journal of neuromuscular diseases · 2018Article
- Introduction to the feature issue on the 25 year anniversary of optical coherence tomography.Biomedical optics express · 2017Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the heart structural remodeling in the mdx4cv mouse model of Duchenne cardiomyopathy using optical polarization tractography. Whole heart tractography was obtained in freshly dissected hearts from six mdx4cv mice. Six hearts from C57BL/6J mice were also imaged as the normal control. The mdx4cv hearts were significantly larger than the control hearts and had significantly higher between-subject variations in myofiber organization. While both strains showed classic cross-helical fiber organization in the left ventricle, the rate of the myocardial fiber orientation change across the heart wall was significantly altered in the right ventricle of the mdx4cv heart.
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