ArticleGreen chemistry : an international journal and green chemistry resource : GC2017
Amine dehydrogenases: efficient biocatalysts for the reductive amination of carbonyl compounds.
Article in Green chemistry : an international journal and green chemistry resource : GC, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Immobilized Wild-Type and Mutant L‑Alanine Dehydrogenase fromACS omega · 2026Article
- Stereoconvergent Photo-Biocatalytic Cascade to Optically Enriched Amines from Racemic Carboxylic Acids.ACS omega · 2026Article
- The Sabatier principle governs the performance of self-sufficient heterogeneous biocatalysts for redox biotransformations.Cell reports. Physical science · 2025Article
- Reversible enzyme-catalysed NADChemical science · 2025Article
- Discovery and Synthetic Applications of a NAD(P)H-Dependent Reductive Aminase fromACS catalysis · 2025Article
- In situ characterization of amine-forming enzymes shows altered oligomeric state.Protein science : a publication of the Protein Society · 2025Article
- Bifunctional Imine Reductase Cascades for the Synthesis of SaturatedACS catalysis · 2024Article
- A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening.Nature communications · 2024Article
- How Can Deep Eutectic Systems Promote Greener Processes in Medicinal Chemistry and Drug Discovery?Pharmaceuticals (Basel, Switzerland) · 2024Review
- Enzymatic Routes for Chiral Amine Synthesis: Protein Engineering and Process Optimization.Biologics : targets & therapy · 2024Review
- The Discovery of Imine Reductases and their Utilisation for the Synthesis of Tetrahydroisoquinolines.ChemCatChem · 2023Article
- Aerobic C-N Bond Formation through Enzymatic Nitroso-Ene-Type Reactions.Angewandte Chemie (International ed. in English) · 2023Article
- One-Pot Biocatalytic Synthesis of Primary, Secondary, and Tertiary Amines with Two Stereocenters from α,β-Unsaturated Ketones Using Alkyl-Ammonium Formate.ACS catalysis · 2022Article
- Article
- High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from l-Phenylalanine via Linear and Divergent Enzymatic Cascades.Organic process research & development · 2022Review
- Review
- Structure and Mutation of the Native Amine Dehydrogenase MATOUAmDH2.Chembiochem : a European journal of chemical biology · 2022Article
- Reductive aminations by imine reductases: from milligrams to tons.Chemical science · 2022Review
- Stereo-Divergent Enzyme Cascades to Convert Racemic 4-Phenyl-2-Butanol into either (S)- or (R)-Corresponding Chiral Amine.Chembiochem : a European journal of chemical biology · 2022Article
- New Trends and Future Opportunities in the Enzymatic Formation of C-C, C-N, and C-O bonds.Chembiochem : a European journal of chemical biology · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Amines constitute the major targets for the production of a plethora of chemical compounds that have applications in the pharmaceutical, agrochemical and bulk chemical industries. However, the asymmetric synthesis of α-chiral amines with elevated catalytic efficiency and atom economy is still a very challenging synthetic problem. Here, we investigated the biocatalytic reductive amination of carbonyl compounds employing a rising class of enzymes for amine synthesis: amine dehydrogenases (AmDHs). The three AmDHs from this study - operating in tandem with a formate dehydrogenase from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.