Evidence map›Paper›PMID 28663633›Full record

ArticleAnesthesia, essays and researches

Comparing the Efficacy of Caudal with Intravenous Dexamethasone in the Management of Pain Following Lumbosacral Spine Surgeries: A Randomized Double Blinded Controlled Study.

Sandhya Kalappa, Raghavendra Biligiri Sridhar, Saraswathi Nagappa

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Anesthesia, essays and researches. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05904275 (A Randomized Case Control Study of Pre-emptive Caudal Epidural Analgesia With Ropivacaine With and Without Dexamethasone for Lumbosacral Spine Surgery), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05904275 naunknown statusnot on this map

A Randomized Case Control Study of Pre-emptive Caudal Epidural Analgesia With Ropivacaine With and Without Dexamethasone for Lumbosacral Spine Surgery

TypeinterventionalSponsorNational Trauma CenterRan2023 to 2024Enrolled60ConditionsPost Operative PainArmscaudal epidural injection
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Adverse side effects of dexamethasone in surgical patients.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Adverse side effects of dexamethasone in surgical patients.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Dexamethasone in anesthesia practice: A narrative review.Journal of anaesthesiology, clinical pharmacology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sandhya KalappaDepartment of Anaesthesia, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
Raghavendra Biligiri SridharDepartment of Anaesthesia, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
Saraswathi NagappaDepartment of Anaesthesia, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
Bangalore Medical College and Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe challenge in providing analgesia for spine surgeries is to provide extended postoperative pain relief and simultaneously allow early neurological assessment and mobilization. Our study aimed to evaluate the analgesic efficacy of intravenous versus caudal dexamethasone in lumbosacral spine surgeries. MATERIALS AND

methodsIn this prospective double-blind study, a total of 96 patients undergoing lumbosacral spine surgery were randomized into three groups to receive 25 ml of preemptive caudal epidural injection of either injection ropivacaine 0.2% (Group A,

resultsThe mean VAS was significantly lower in the Group C for up to 24 h following the caudal block. No significant hemodynamic changes were noted in any of the groups. The intravenous dexamethasone group showed higher blood glucose levels at 24 h but was not clinically relevant.

conclusionThese results suggest that injection dexamethasone is a safe adjunct to caudal ropivacaine in lumbosacral spine surgeries.

Indexed as

Analgesiacaudaldexamethasoneintravenouspostoperative painropivacainespine surgeriessteroids

Identifiers

PMID28663633
PMCPMC5490116
OpenAlexW2614666326

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.