ArticleScientific reports2017
A Simple and Rapid Turn On ESIPT Fluorescent Probe for Colorimetric and Ratiometric Detection of Biothiols in Living Cells.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 55 citations in OpenAlex.
- Theoretical Study on the Photophysical Mechanism for the Detection of Biothiols Based on the 1,3,4-Thiadiazole Fluorescence Probe.Journal of fluorescence · 2026Article
- Heterocyclic molecules with ESIPT emission: synthetic approaches, molecular diversities, and application strategies.Turkish journal of chemistry · 2023Review
- Self-Assembled Lanthanide Antenna Glutathione Sensor for the Study of Immune Cells.ACS sensors · 2022Article
- An ICT-Based Coumarin Fluorescent Probe for the Detection of Hydrazine and Its Application in Environmental Water Samples and Organisms.Frontiers in bioengineering and biotechnology · 2022Article
- Ratiometric Detection of Glutathione Based on Disulfide Linkage Rupture between a FRET Coumarin Donor and a Rhodamine Acceptor.Chembiochem : a European journal of chemical biology · 2021Article
- Article
- Nile-Red-Based Fluorescence Probe for Selective Detection of Biothiols, Computational Study, and Application in Cell Imaging.Molecules (Basel, Switzerland) · 2020Article
- Sensing mechanism of a ratiometric near-infrared fluorescent chemosensor for cysteine hydropersulfide: Intramolecular charge transfer.Scientific reports · 2020Article
- A novel and simple imidazo[1,2-a]pyridin fluorescent probe for the sensitive and selective imaging of cysteine in living cells and zebrafish.Analytica chimica acta · 2019Article
- Interactions of Bromocarbazoles with Human Serum Albumin Using Spectroscopic Methods.Molecules (Basel, Switzerland) · 2018Article
- A Hybrid Coumarin-Semifluorescein-Based Fluorescent Probe for the Detection of Cysteine.Journal of fluorescence · 2018Article
- Selective Screening of Biological Thiols by Means of an Unreported Magenta Interaction and Evaluation Using Smartphones.ACS omega · 2018Article
- Nanoscale gizmos - the novel fluorescent probes for monitoring protein activity.Biochemical engineering journal · 2018Review
- A Turn-On Fluorescent Probe for Sensitive Detection of Cysteine in a Fully Aqueous Environment and in Living Cells.Journal of analytical methods in chemistry · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biothiols, such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play a key role in an extensive range of physiological processes and biological functions. Therefore, the selective and sensitive detection of intracellular thiols is important for revealing cellular function. In this study, ethyl 2-(4-(acryloyloxy)-3-formylphenyl)-4-methylthiazole-5-carboxylate (NL-AC) was designed and synthesized as a colorimetric and ratiometric fluorescent probe that can be utilized to rapidly, sensitively and selectively detect biothiols in physiological media. The fluorescence intensity of this probe using the three target biothiols at a concentration of 20 equiv. of the probe increased by approximately 6~10-fold in comparison to that without the biothiols in aqueous solution. The limits of detection (LOD) for Cys, Hcy and GSH were 0.156, 0.185, and 1.838 μM, respectively. In addition, both
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Registered trials
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