Evidence map›Paper›PMID 28663374›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017

Extra- and intracranial blood flow regulation during the cold pressor test: influence of age.

Daniela Flück, Philip N Ainslie, Anthony R Bain, Kevin W Wildfong, Laura E Morris, James P Fisher

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Between-visit reproducibility of cerebrovascular and cardiovascular reactivity during the cold pressor test.American journal of physiology. Heart and circulatory physiology · 2026
    Article
  4. Article
  5. Article
  6. Cold Pressor Test Induces Significant Changes in Internal Jugular Vein Flow Dynamics in Healthy Young Adults.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  7. Contrast-enhanced ultrasonography reveals a lower cortical perfusion and a decreased renal flow reserve in hypertensive patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Daniela FlückCentre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan, Kelowna, British Columbia, Canada; and daniela.flueck@ubc.ca.ORCID http://orcid.org/0000-0001-8545-2556
Philip N AinslieCentre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan, Kelowna, British Columbia, Canada; and.
Anthony R BainCentre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan, Kelowna, British Columbia, Canada; and.
Kevin W WildfongCentre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan, Kelowna, British Columbia, Canada; and.
Laura E MorrisCentre for Heart, Lung, and Vascular Health, School of Health and Exercise Sciences, University of British Columbia - Okanagan, Kelowna, British Columbia, Canada; and.
James P FisherSchool of Sport, Exercise, and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0001-7851-9222
University of British Columbia · CAUniversity of Birmingham · GB

Funding

British Heart Foundation PG/15/45/31579
6 · The paper itself

Abstract

We determined how the extra- and intracranial circulations respond to generalized sympathetic activation evoked by a cold pressor test (CPT) and whether this is affected by healthy aging. Ten young [23 ± 2 yr (means ± SD)] and nine older (66 ± 3 yr) individuals performed a 3-min CPT by immersing the left foot into 0.8 ± 0.3°C water. Common carotid artery (CCA) and internal carotid artery (ICA) diameter, velocity, and flow were simultaneously measured (duplex ultrasound) along with middle cerebral artery and posterior cerebral artery mean blood velocity (MCAv

Indexed as

Cerebrovascular CirculationCold TemperatureImmersionWaterAdaptation, PhysiologicalAdultAgedBlood Flow VelocityBlood PressureCarotid Artery, CommonCarotid Artery, InternalFootHeart RateHumansMiddle AgedMiddle Cerebral ArteryWaterbrain blood flowelderlysympathetic nerve activity

Identifiers

PMID28663374
PMCPMC5792099
OpenAlexW2730157814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.