Evidence map›Paper›PMID 28663368›Full record

ArticleThe Journal of biological chemistry2017

Betaine is accumulated via transient choline dehydrogenase activation during mouse oocyte meiotic maturation.

Taylor McClatchie, Megan Meredith, Mariame O Ouédraogo, Sandy Slow, Michael Lever, Mellissa R W Mann, Steven H Zeisel, Jacquetta M Trasler, Jay M Baltz

Erratum issuedOpen access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Taylor McClatchieFrom the Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada.
Megan MeredithFrom the Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada.
Mariame O OuédraogoFrom the Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada.
Sandy Slowthe Department of Pathology, University of Otago, Christchurch 8140, New Zealand.
Michael Leverthe Department of Chemistry, University of Canterbury, Christchurch 8041, New Zealand.
Mellissa R W Mannthe Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213.ORCID 0000-0002-8075-3824
Steven H Zeiselthe Department of Nutrition, Nutrition Research Institute, Gillings School of Global Public Health and School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599.ORCID 0000-0002-9282-161X
Jacquetta M Traslerthe Montréal Children's Hospital and Research Institute of the McGill University Health Centre, Montréal, Quebec H4A 3J1, Canada, and.
Jay M BaltzFrom the Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada, jbaltz@ohri.ca.ORCID 0000-0002-9749-2480
University of Ottawa · CAMontreal Children's Hospital · CAUniversity of Canterbury · NZUniversity of North Carolina at Chapel Hill · USUniversity of Otago · NZUniversity of Pittsburgh · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
CIHR MOP97972NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

Betaine (

Indexed as

OogenesisUp-RegulationAbsorption, PhysiologicalAnimalsBetaineBlastocystCholine DehydrogenaseCrosses, GeneticEnzyme ActivationFemaleGene Expression Regulation, DevelopmentalIn Vitro Oocyte Maturation TechniquesMeiosisMiceMice, Inbred C57BLMice, KnockoutBetaineCholine DehydrogenaseTritiumbetainecholinecholine dehydrogenaseenzymegene knockoutmeiosismouseoocyte

Identifiers

PMID28663368
PMCPMC5566531
OpenAlexW2731254637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.