Evidence map›Paper›PMID 28663349›Full record

Observational studyArchives of disease in childhood2017

A nationwide cohort study of slipped capital femoral epiphysis.

Daniel C Perry, David Metcalfe, Matthew L Costa, Tjeerd Van Staa

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Archives of disease in childhood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 69 citations in OpenAlex.

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  5. Slipped capital femoral epiphysis (SCFE) a structured approach for the FRCS examination.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Daniel C PerryInstitute of Translational Medicine, University of Liverpool, Liverpool, UK.
David MetcalfeNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK.
Matthew L CostaNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, UK.
Tjeerd Van StaaHealth eResearch Centre, University of Manchester, Manchester, UK.
Manchester Academic Health Science Centre · GBNuffield Orthopaedic Centre · GBUniversity of Liverpool · GBUniversity of Oxford · GB

Funding

Arthritis Research UKBritish Heart FoundationDepartment of Health CS-2014-14-012Medical Research Council MC_PC_13042Medical Research Council MR/K006665/1Wellcome Trust
6 · The paper itself

Abstract

objectivesTo describe the epidemiology of slipped capital femoral epiphysis (SCFE), to examine associations with childhood obesity and socioeconomic deprivation, and to explore factors associated with diagnostic delays.

designHistoric cohort study using linked primary and secondary care data from the Clinical Practice Research Datalink and Hospital Episode Statistics.

settingAll contacts with healthcare services, including emergency presentations, outpatient appointments, inpatient admissions and primary care visits, within the UK National Health Service. PATIENTS: All individuals <16 years old with a diagnosis of SCFE and whose electronic medical record was held by one of 650 primary care practices in the UK between 1990 and 2013.

main outcome measuresAnnual incidence, missed opportunities for diagnosis and diagnostic delay.

resultsOver the 23-year period the incidence remained constant at 4.8 (95% CI 4.4 to 5.2) cases per 100,000 0-16-year-olds. There was a strong association with socioeconomic deprivation. Predisease obesity was also strongly associated with SCFE; mean predisease z-score of body mass index was 1.43 (95% CI 1.20 to 1.68) compared with the UK reference mean. Diagnostic delays were common, with most children (75.4%) having multiple primary care contacts with relevant symptomatology, and those who presented with knee pain having significantly longer diagnostic delay (median 161 (IQR 27-278) days) than those with hip pain (20 (5-126)) or gait abnormalities (21 (7-72)).

conclusionsSCFE has a strong association with both area-level socioeconomic deprivation and predisease obesity. The majority of patients with SCFE are initially misdiagnosed and those presenting with knee pain are particularly at risk.

Indexed as

AdolescentAge of OnsetBody Mass IndexChildChild, PreschoolCohort StudiesComorbidityDatabases, FactualDelayed DiagnosisDiagnostic ErrorsEnglandFemaleHumansIncidenceInfantInfant, Newborndelayed diagnosisdescriptive epidemiologymisdiagnosisslipped capital femoral epiphyses

Identifiers

PMID28663349
PMCPMC5754864
OpenAlexW2729567711

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.