Evidence map›Paper›PMID 28663335›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2017

Mitochondrial quality control in alveolar epithelial cells damaged by

Hagir B Suliman, Bryan Kraft, Raquel Bartz, Lingye Chen, Karen E Welty-Wolf, Claude A Piantadosi

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. The mitophagy pathway and its implications in human diseases.Signal transduction and targeted therapy · 2023
    Review
  15. Mitochondrial Dysfunction in Bacterial Infections.Pathogens (Basel, Switzerland) · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hagir B SulimanDepartments of Medicine, Pathology, and Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Bryan KraftDepartments of Medicine, Pathology, and Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Raquel BartzDepartments of Medicine, Pathology, and Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Lingye ChenDepartments of Medicine, Pathology, and Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Karen E Welty-WolfDepartments of Medicine, Pathology, and Anesthesiology, Duke University Medical Center, Durham, North Carolina.
Claude A PiantadosiDepartments of Medicine, Pathology, and Anesthesiology, Duke University Medical Center, Durham, North Carolina piant001@mc.duke.edu.
Duke Medical Center · US

Funding

Mesenchymal Stromal Cell Conditioning by Carbon MonoxideP01HL108801 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SERHAN, CHARLES NICHOLAS · 2011 to 2015
$13.8M
Mitochondrial quality control and alveolar damage resolution after acute lung injuryR01HL135239 · NHLBI · DUKE UNIVERSITY · PI WELTY-WOLF, KAREN E · 2017 to 2020
$1.6M
Role of S-nitrosothiols in Akt1 signaling and pneumonia resolutionK08HL130557 · NHLBI · DUKE UNIVERSITY · PI KRAFT, BRYAN D. · 2017 to 2021
$591k
BLRD VA I01 BX004289NHLBI NIH HHS K08 HL130557NHLBI NIH HHS P01 HL108801NHLBI NIH HHS R01 HL135239
6 · The paper itself

Abstract

Mitochondrial damage is often overlooked in acute lung injury (ALI), yet most of the lung's physiological processes, such as airway tone, mucociliary clearance, ventilation-perfusion (Va/Q) matching, and immune surveillance require aerobic energy provision. Because the cell's mitochondrial quality control (QC) process regulates the elimination and replacement of damaged mitochondria to maintain cell survival, we serially evaluated mitochondrial biogenesis and mitophagy in the alveolar regions of mice in a validated

Indexed as

Alveolar Epithelial CellsAnimalsApoptosisBiomarkersMaleMiceMice, Inbred C57BLMitochondriaPneumonia, StaphylococcalStaphylococcal InfectionsStaphylococcus aureusBiomarkersacute lung injuryalveolar epithelial cellsmitochondriamitophogyquality control

Identifiers

PMID28663335
PMCPMC6148085
OpenAlexW2729883220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.