ArticleJournal of the American Heart Association2017
Association Between Elevated Pulse Pressure and High Resting Coronary Blood Flow Velocity in Patients With Angiographically Normal Epicardial Coronary Arteries.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Clinical applications of resting coronary flow detection via transthoracic echocardiography.Frontiers in cardiovascular medicine · 2025Review
- Obesity: the perfect storm for heart failure.ESC heart failure · 2024Review
- The role of stress echocardiography in identifying cardiotoxicity: an in-depth exploration.Frontiers in cardiovascular medicine · 2024Review
- Prognostic Value of Modified Coronary Flow Capacity Derived From [Circulation. Cardiovascular imaging · 2023Article
- Hypertension-mediated organ damage involving multiple sites is an independent risk factor for cardiovascular events.European heart journal open · 2023Article
- A spatiotemporal analysis of the left coronary artery biomechanics using fluid-structure interaction models.Medical & biological engineering & computing · 2023Article
- From Structural to Functional Hypertension Mediated Target Organ Damage-A Long Way to Heart Failure with Preserved Ejection Fraction.Journal of clinical medicine · 2022Review
- Low mechano-energetic efficiency is associated with future left ventricular systolic dysfunction in hypertensives.ESC heart failure · 2022Article
- Fluid shear stress enhances T cell activation through Piezo1.BMC biology · 2022Article
- Article
- Advanced imaging tools for evaluating cardiac morphological and functional impairment in hypertensive disease.Journal of hypertension · 2022Review
- Determinants of improvement of left ventricular mechano-energetic efficiency in hypertensive patients.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of our study was to evaluate the relationship of pulse pressure (PP), a raw index of arterial stiffness, with noninvasively determined coronary flow reserve (CFR) and its components, in patients with angiographically normal epicardial coronary arteries. METHODS AND
resultsThe study population included 398 patients without angiographic evidence of coronary stenosis, who underwent high-dose dipyridamole stress echocardiography with transthoracic-derived CFR evaluation on the left anterior descending artery. CFR was calculated as the ratio between high-dose dipyridamole and resting coronary diastolic peak velocities. Patients were divided into 2 groups: the first group included the first and second PP tertiles (n=298, PP ≤60 mm Hg) and the second group included the highest PP tertile (n=100, PP >60 mm Hg). Mean blood pressure, systolic blood pressure (both
conclusionsIn patients without epicardial coronary artery stenosis, the highest PP tertile is associated with an increased coronary flow velocity at rest.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.