ArticleDrug and alcohol dependence2017
Association between process measures and mortality in individuals with opioid use disorders.
Article in Drug and alcohol dependence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Comparison of buprenorphine treatment by virtual-only vs. traditional clinicians.Journal of substance use and addiction treatment · 2026Article
- Contexts for Scaling Up Evidence-Based Preventive Interventions: Examining Factors That Influence the Likelihood of the Use of Research Language in Substance Use Legislation.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Integration of pharmacotherapy for alcohol use disorder treatment in primary care settings: A scoping review.Journal of substance abuse treatment · 2023Article
- Patient-centered quality measurement for opioid use disorder: Development of a taxonomy to address gaps in research and practice.Substance abuse · 2022Review
- A mixed methods study of provider factors in buprenorphine treatment retention.The International journal on drug policy · 2022Article
- Linking Process and Outcome Measures to Improve Employment Support Programs for Individuals With the Most Significant Disabilities.Frontiers in rehabilitation sciences · 2022Article
- Financial sustainability of payment models for office-based opioid treatment in outpatient clinics.Addiction science & clinical practice · 2021Review
- Primary Care Providers And Specialists Deliver Comparable Buprenorphine Treatment Quality.Health affairs (Project Hope) · 2020Article
- Defining a recovery-oriented cascade of care for opioid use disorder: A community-driven, statewide cross-sectional assessment.PLoS medicine · 2019Article
- Innovative Solutions for State Medicaid Programs to Leverage Their Data, Build Their Analytic Capacity, and Create Evidence-Based Policy.EGEMS (Washington, DC) · 2019Article
- A Quality Framework for Emergency Department Treatment of Opioid Use Disorder.Annals of emergency medicine · 2019Article
- Developing an opioid use disorder treatment cascade: A review of quality measures.Journal of substance abuse treatment · 2018Review
- Moving Addiction Care to the Mainstream - Improving the Quality of Buprenorphine Treatment.The New England journal of medicine · 2018Article
- Measuring and improving the quality of mental health care: a global perspective.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018Article
- Commentary: Applying the Community Partners in Care Approach to the Opioid Crisis.Ethnicity & disease · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundIndividuals with opioid use disorders have high rates of mortality relative to the general population. The relationship between treatment process and mortality is unknown.
aimTo examine the association between 7 process measures and 12- and 24-month mortality.
methodsRetrospective cohort study of patients with opioid use disorders who received care from the Veterans Administration between October 2006 and September 2007. Logistic regression models were used to examine the association between 12 and 24-month mortality and 7 patient-level process measures, while risk-adjusting for patient characteristics. Process measures included quarterly physician visits, any opioid use disorder pharmacotherapy, continuous pharmacotherapy, psychosocial treatment, Hepatitis B/C and HIV screening, and no prescriptions for benzodiazepines or opioids. We conducted sensitivity analyses to examine the robustness of our findings to an unobserved confounder.
resultsAmong individuals with opioid use disorders, not being prescribed opioids or benzodiazepines, receipt of any psychosocial treatment and quarterly physician visits were significantly associated with lower mortality at both 12 and 24 months, but Hepatitis and HIV screening, and measures related to opioid use disorder pharmacotherapy were not. Sensitivity analyses indicated that the difference in the prevalence of an unobserved confounder would have to be unrealistically large given the observed data, or there would need to be a large effect of the confounder, to render these findings non-significant. CONCLUSIONS AND RELEVANCE: This is the first study to show an association between process measures and mortality in patients with opioid use disorders and provides initial evidence for their use as quality measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.