Evidence map›Paper›PMID 28662727›Full record

ArticleJournal of neuroengineering and rehabilitation2017

Frontal brain activation changes due to dual-tasking under partial body weight support conditions in older adults with multiple sclerosis.

Gioella Chaparro, Julia M Balto, Brian M Sandroff, Roee Holtzer, Meltem Izzetoglu, Robert W Motl, Manuel E Hernandez

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Article in Journal of neuroengineering and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Observational
  9. Brain Connectivity During Walking and Obstacle Avoidance in Persons With Multiple Sclerosis and Healthy Controls: A Pilot EEG Study.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gioella ChaparroDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Julia M BaltoDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Brian M SandroffDepartment of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.
Roee HoltzerDepartment of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.
Meltem IzzetogluSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA, USA.
Robert W MotlDepartment of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.
Manuel E HernandezDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Champaign, IL, USA. mhernand@illinois.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGait impairments present while dual-tasking in older adults with multiple sclerosis (MS) have been associated with an increased risk of falls. Prior studies have examined prefrontal cortex (PFC) activity using functional near infrared spectroscopy (fNIRS) while dual-tasking in older adults with and without cognitive impairment. While the benefits of partial body weight support (PBWS) on gait have been clearly outlined in the literature, the potential use of PBWS to improve the ability to dual task in older adults with and without MS has not been examined. The aim of this study was to examine the effects of PBWS on the PFC activation while dual-tasking in older adults with and without MS.

methodsTen individuals with MS (mean 56.2 ± 5.1 yrs., 8 females) and 12 healthy older adults (HOA) (mean 63.1 ± 4.4 yrs., 9 females) participated in this study. PFC activation (i.e., oxygenated hemoglobin-HbO

resultsHbO

conclusionsThis study establishes the potential impact of PBWS on PFC activation patterns under dual-tasking conditions and sheds light on the ability for PBWS to be used as a therapeutic tool in individuals with neurological conditions to decrease cognitive demands while dual-tasking and thus decrease the risk of falls.

Indexed as

AgedBody WeightCognitionCohort StudiesFemaleFrontal LobeGaitHealthy VolunteersHemoglobinsHumansMaleMiddle AgedMotor SkillsMultiple SclerosisNeuroimagingNeuropsychological TestsHemoglobinsAttentionFunctional neuroimagingGaitMultiple sclerosisWeight-bearing

Identifiers

PMID28662727
PMCPMC5493004

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.