ArticleBMC oral health2017
Oral symptoms and salivary findings in oral lichen planus, oral lichenoid lesions and stomatitis.
Article in BMC oral health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- "Exploring the Link Between Oral Lichen Planus and Xerostomia: A Systematic Literature Review".Immunity, inflammation and disease · 2024Pooled it
- Serum and Salivary IgA, IgG, and IgM Levels in Oral Lichen Planus: A Systematic Review and Meta-Analysis of Case-Control Studies.Medicina (Kaunas, Lithuania) · 2018Pooled it
- Assessment of Anti-M3R antibody in patients with oral lichen planus complaining of xerostomia: a preliminary study.BMC oral health · 2026Article
- Anti-M3 Muscarinic Acetylcholine Receptor Autoantibody in the Serum and Saliva of Oral Lichen Planus Patients: A Case-Control Study.Health science reports · 2026Article
- Unraveling the causal association of epigenetic age acceleration with common oral diseases and its underlying mechanisms: findings from Mendelian randomization and integrative genetic analysis.Clinical epigenetics · 2025Article
- Evaluation of salivary nitric oxide levels and anxiety in multiple sclerosis patients, with and without Xerostomia: correlation with clinical variables.BMC oral health · 2025Observational
- Whitening toothpaste-induced oral mucosal hypersensitivity reaction resembling oral lichenoid reaction: a clinically diagnosed case report.Frontiers in oral health · 2025Article
- Salivary Histamine Levels in Patients with Oral Lichen Planus Lesions.Medicina (Kaunas, Lithuania) · 2024Article
- The relationship between clinical symptoms of oral lichen planus and quality of life related to oral health.BMC oral health · 2024Article
- HPV related p16BMC oral health · 2024Article
- Patients with oral lichen planus display lower levels of salivary acidic glycoproteins than individuals without oral mucosal disease.Clinical oral investigations · 2023Article
- The prevalence of contact hypersensitivity in patients with oral lichen planus.Postepy dermatologii i alergologii · 2022Article
- Review
- Association between Clinical Signs of Oral Lichen Planus and Oral Health-Related Quality of Life: A Preliminary Study.Dentistry journal · 2020Article
- Putative salivary protein biomarkers for the diagnosis of oral lichen planus: a case-control study.BMC oral health · 2018Article
- Serum cytokine profile and clinicopathological findings in oral lichen planus, oral lichenoid lesions and stomatitis.Clinical and experimental dental research · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo examine if patients with oral lichen planus, oral lichenoid lesions and generalised stomatitis and concomitant contact allergy have more frequent and severe xerostomia, lower unstimulated and chewing-stimulated saliva and citric-acid-stimulated parotid saliva flow rates, and higher salivary concentration of total protein and sIgA than cases without contact allergy and healthy controls.
methodsForty-nine patients (42 women, aged 61.0 ± 10.3 years) and 29 healthy age- and gender-matched subjects underwent a standardised questionnaire on general and oral health, assessment of xerostomia, clinical examination, sialometry, mucosal biopsy and contact allergy testing.
resultsNineteen patients had oral lichen planus, 19 patients had oral lichenoid lesions and 11 patients had generalised stomatitis. 38.8% had contact allergy. Xerostomia was significantly more common and severe in patients (46.9%) than in healthy controls, whereas the saliva flow rates did not differ. The patients had higher sIgA levels in unstimulated and chewing-stimulated saliva than the healthy controls. The total protein concentration in saliva was lower in the unstimulated saliva samples whereas it was higher in the chewing stimulated saliva samples from patients when compared to healthy controls. The differences were not significant and they were irrespective of the presence of contact allergy.
conclusionXerostomia is prevalent in patients with oral lichen planus, lichenoid lesions and generalised stomatitis, but not associated with salivary gland hypofunction, numbers of systemic diseases or medications, contact allergy, age, or gender. Salivary sIgA levels were higher in patients than in healthy controls, but did not differ between patient groups. The total salivary protein concentration was lower in unstimulated saliva samples and higher in chewing-stimulated saliva samples in patients than in healthy controls, but did not differ between patient groups. Our findings do not aid in the discrimination between OLP and OLL and these conditions with or without contact allergic reactions.
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