Evidence map›Paper›PMID 28662661›Full record

ArticleBMC biology2017

Non-model model organisms.

James J Russell, Julie A Theriot, Pranidhi Sood, Wallace F Marshall, Laura F Landweber, Lillian Fritz-Laylin, Jessica K Polka, Snezhana Oliferenko, Therese Gerbich, Amy Gladfelter and 9 more

Abstract read
In one paragraph

Article in BMC biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Evaluating the Validity of Model Organisms: A Review and a New Framework for Biologists.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Modeling versatility as the hallmark of model organisms.History and philosophy of the life sciences · 2026
    Article
  8. Review
  9. Reflections on Model Species in Evolutionary Developmental Biology.Results and problems in cell differentiation · 2026
    Review
  10. Article
  11. Elucidation of the growth phenotypes of 82 strains from theFrontiers in bioengineering and biotechnology · 2026
    Article
  12. Article
  13. Evolutionary cell biology comes of age.Journal of cell science · 2025
    Article
  14. Article
  15. Article
  16. bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

James J RussellDepartment of Biology, Howard Hughes Medical Institute Stanford University, Stanford, CA, 94305, USA.
Julie A TheriotDepartments of Biochemistry and of Microbiology & Immunology, Howard Hughes Medical Institute Stanford University, Stanford, CA, 94305, USA. theriot@stanford.edu.
Pranidhi SoodDepartment of Biochemistry & Biophysics, University of California San Francisco, 600 16th St, San Francisco, CA, 94158, USA.
Wallace F MarshallDepartment of Biochemistry & Biophysics, University of California San Francisco, 600 16th St, San Francisco, CA, 94158, USA. Wallace.marshall@ucsf.edu.
Laura F LandweberDepartments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY, 10032, USA.
Lillian Fritz-LaylinDepartment of Biology, University of Massachusetts, Amherst, MA, 01003, USA.
Jessica K PolkaVisiting Scholar, Whitehead Institute, 9 Cambridge Center, Cambridge, MA, 02142, USA.
Snezhana OliferenkoThe Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
Therese Gerbich516 Fordham Hall, University of North Carolina Chapel Hill, Chapel Hill, NC, 27514, USA.
Amy Gladfelter516 Fordham Hall, University of North Carolina Chapel Hill, Chapel Hill, NC, 27514, USA.
James UmenDonald Danforth Plant Science Center, 975 N. Warson Rd, St. Louis, MO, 63132, USA.
Magdalena BezanillaDepartment of Biology, University of Massachusetts, Amherst, MA, 01003, USA.
Madeline A LancasterMRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, CB2 0QH, Cambridge, UK.
Shuonan HeStowers Institute for Medical Research, Kansas City, MO, 64110, USA.
Matthew C GibsonStowers Institute for Medical Research, Kansas City, MO, 64110, USA.
Bob GoldsteinBiology Department, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Elly M TanakaResearch Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus Vienna Biocenter 1, 1030, Vienna, Austria.
Chi-Kuo HuDepartment of Genetics, Stanford University, Stanford, CA, 94305, USA.
Anne BrunetDepartment of Genetics, Stanford University, Stanford, CA, 94305, USA.

Funding

Leveraging innovative technologies in basic and clinical cancer researchT32CA009302 · NCI · STANFORD UNIVERSITY · PI LAURA D ATTARDI, Aaron M Newman · 1985 to 2026
$19.1M
TRAINING & OUTREACH COREP50GM107615 · NIGMS · STANFORD UNIVERSITY · PI FERRELL, JAMES E. · 2013 to 2017
$10.9M
Understanding Complex Genome Editing and RNA Biology in OxytrichaR35GM122555 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LAURA F LANDWEBER · 2017 to 2026
$7.9M
Transgenerational epigenetic inheritance of longevityDP1AG044848 · NIA · STANFORD UNIVERSITY · PI BRUNET, ANNE · 2012 to 2016
$3.9M
Actin-Based Motility of a Bacterial PathogenR37AI036929 · NIAID · UNIVERSITY OF WASHINGTON · PI THERIOT, JULIE A. · 2010 to 2019
$3.0M
Pattern formation and regeneration in a single cellR01GM113602 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARSHALL, WALLACE · 2015 to 2018
$1.6M
Medical Research Council MC_UP_1201/9NCI NIH HHS T32 CA009302NIA NIH HHS DP1 AG044848NIGMS NIH HHS R01 GM113602Wellcome TrustWellcome Trust 103741/Z/14/Z
6 · The paper itself

Abstract

Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to extend the set of model organisms to include less-studied and more unusual systems. This Forum highlights a range of 'non-model model organisms' as emerging systems for tackling questions across the whole spectrum of biology (and beyond), the opportunities and challenges, and the outlook for the future.

Indexed as

BiologyEukaryotaModels, AnimalAnimalsPlants

Identifiers

PMID28662661
PMCPMC5492503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.