ArticlePloS one2017
Bacterial microbiome in the nose of healthy cats and in cats with nasal disease.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 51 citations in OpenAlex.
- First Description of Oral Microbiota in Domestic Cats Affected by Oral Squamous Cell Carcinoma.Pathogens (Basel, Switzerland) · 2026Article
- Natural Microbiota of Dogs and Cats as a Source and Vector of Resistance Genes-Clinical Significance.International journal of molecular sciences · 2025Review
- Microbial Interconnections in One Health: A Critical Nexus Between Companion Animals and Human Microbiomes.Microorganisms · 2025Review
- Species diversity, virulence, and antimicrobial resistance of the nasal staphylococcal and mammaliicoccal biota of reindeer.BMC veterinary research · 2025Article
- Frontal Sinus Trephination and Repeated Irrigation in a Cat with Chronic Rhinosinusitis: A Case Report.Animals : an open access journal from MDPI · 2025Article
- Six-year duration of upper respiratory tract signs in a cat secondary to a draining tract from an incomplete enucleation in the left orbit.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
- Decoding the Gut Microbiome in Companion Animals: Impacts and Innovations.Microorganisms · 2024Review
- Characteristics of gallbladder microbiome in healthy dogs and cats, dogs with gallbladder mucocele, and cats with suspected cholangitis/cholangiohepatitis.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2024Article
- CanineMicrobiology spectrum · 2024Article
- Feline respiratory disease complex: insights into the role of viral and bacterial co-infections.Frontiers in microbiology · 2024Article
- Bacterial Contamination of Inhalation Chambers Used for Cats and Dogs with Chronic Airway Diseases.Pathogens (Basel, Switzerland) · 2023Article
- Comparative Analyses of the Gut Microbiota in Growing Ragdoll Cats and Felinae Cats.Animals : an open access journal from MDPI · 2022Article
- Investigation of Bacterial Isolations and Antimicrobial Susceptibility of Chronic Rhinitis in Cats.Animals : an open access journal from MDPI · 2022Article
- Perspectives and advances in probiotics and the gut microbiome in companion animals.Journal of animal science and technology · 2022Review
- Article
- Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs.BMC veterinary research · 2021Article
- Characterization of Oral Microbiota in Cats: Novel Insights on the Potential Role of Fungi in Feline Chronic Gingivostomatitis.Pathogens (Basel, Switzerland) · 2021Article
- Social environment and genetics underlie body site-specific microbiomes of Yellowstone National Park gray wolves (Ecology and evolution · 2021Article
- Feline conjunctival microbiota in a shelter: effects of time, upper respiratory disease and famciclovir administration.Journal of feline medicine and surgery · 2021Article
- Microbiome analysis of feline odontoclastic resorptive lesion (FORL) and feline oral health.Journal of medical microbiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraditionally, changes in the microbial population of the nose have been assessed using conventional culture techniques. Sequencing of bacterial 16S rRNA genes demonstrated that the human nose is inhabited by a rich and diverse bacterial microbiome that cannot be detected using culture-based methods. The goal of this study was to describe the nasal microbiome of healthy cats, cats with nasal neoplasia, and cats with feline upper respiratory tract disease (FURTD). METHODOLOGY/PRINCIPAL
findingsDNA was extracted from nasal swabs of healthy cats (n = 28), cats with nasal neoplasia (n = 16), and cats with FURTD (n = 15), and 16S rRNA genes were sequenced. High species richness was observed in all samples. Rarefaction analysis revealed that healthy cats living indoors had greater species richness (observed species p = 0.042) and Shannon diversity (p = 0.003) compared with healthy cats living outdoors. Higher species richness (observed species p = 0.001) and Shannon diversity (p<0.001) were found in middle-aged cats in comparison to healthy cats in different age groups. Principal coordinate analysis revealed separate clustering based on similarities in bacterial molecular phylogenetic trees of 16S rRNA genes for indoor and outdoor cats. In all groups examined, the most abundant phyla identified were Proteobacteria, Firmicutes, and Bacteroidetes. At the genus level, 375 operational taxonomic units (OTUs) were identified. In healthy cats and cats with FURTD, Moraxella spp. was the most common genus, while it was unclassified Bradyrhizobiaceae in cats with nasal neoplasia. High individual variability was observed.
conclusionThis study demonstrates that the nose of cats is inhabited by much more variable and diverse microbial communities than previously shown. Future research in this field might help to develop new diagnostic tools to easily identify nasal microbial changes, relate them to certain disease processes, and help clinicians in the decision process of antibiotic selection for individual patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.