ReviewBlood transfusion = Trasfusione del sangue2017
Red blood cell transfusion policy: a critical literature review.
Review in Blood transfusion = Trasfusione del sangue, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Restrictive versus Liberal blood transfusion strategies for patients undergoing orthopedic surgery: a meta-analysis of randomised trials with trial sequential analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Red blood cell alloimmunisation in transfusion-dependent thalassaemia: a systematic review.Blood transfusion = Trasfusione del sangue · 2019Pooled it
- Safety and efficacy of tranexamic acid for prevention of obstetric haemorrhage: an updated systematic review and meta-analysis.Blood transfusion = Trasfusione del sangue · 2018Pooled it
- Safety of intravenous tranexamic acid in patients undergoing majororthopaedic surgery: a meta-analysis of randomised controlled trials.Blood transfusion = Trasfusione del sangue · 2018Pooled it
- Intramedullary administration of tranexamic acid reduces bleeding in proximal femoral nail antirotation surgery for intertrochanteric fractures in elderly individuals: A randomized controlled trial.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Trial
- Comparison of liberal versus restrictive transfusion strategies after hip surgery in patients with coronary artery disease: a post hoc analysis of the FOCUS trial.BMC cardiovascular disorders · 2024Trial
- On the relevance of preoperative haemoglobin optimisation within a Patient Blood Management programme for elective hip arthroplasty surgery.Blood transfusion = Trasfusione del sangue · 2020Trial
- Cost-effectiveness analysis of ferric carboxymaltose in pre-operative haemoglobin optimisation in patients undergoing primary knee arthroplasty.Blood transfusion = Trasfusione del sangue · 2018Trial
- An innovative modelling proposal for the blood supply chain.Vox sanguinis · 2026Review
- Clinical utility of the Oakland score in rectal bleeding: Implications for admission decisions and cost efficiency.International journal of colorectal disease · 2026Article
- Vaginoscopy approach with Mechanical Tissue Removal System for AUB inPediatric Aplastic Anemia: a case report.BMC surgery · 2025Article
- Blood transfusion in older surgical patients: the only option or is there a better approach?Aging clinical and experimental research · 2025Review
- Synergistic Effects of a Novel Combination of Natural Compounds Prevent HInternational journal of molecular sciences · 2025Article
- Myoglobin saturation as an intracellular indicator for transfusion need in oncology patients.Transfusion medicine (Oxford, England) · 2025Article
- Management of severe traumatic brain injury in pediatric patients: an evidence-based approach.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Restrictive versus liberal transfusion thresholds: lights and shadows.Blood transfusion = Trasfusione del sangue · 2025Article
- Exploring the Intersection of Blood Transfusion and Same-Day Computed Tomography Imaging: An Overview of Clinical Risks and Practices.Diagnostics (Basel, Switzerland) · 2024Review
- Navigating anemia and anticoagulation in elderly patients undergoing orthopedic surgery: strategies for preventing complications and implementing treatments.Blood transfusion = Trasfusione del sangue · 2024Review
- Improving normothermic machine perfusion and blood transfusion through biocompatible blood silicification.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Management of an undetectable Diverticular Bleed: A Case Report and Literature review.Clinical case reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The issue of the most appropriate red blood cell transfusion policy has been addressed by a number of randomised controlled trials, conducted over the last decades, comparing the effects on patients' outcome of restrictive blood transfusion strategies (transfusing when the haemoglobin concentration is less than 7 g/dL to 8 g/dL) vs more liberal ones (transfusing when the haemoglobin concentration is less than 9 g/dL to 10 g/dL) in a variety of clinical settings. In parallel, various systematic reviews and meta-analyses have tried to perform pooled analyses of the data from these randomised controlled trials and their results have been utilised by scientific societies to provide recommendations and guidelines on red blood cell transfusion thresholds. All these aspects will be critically discussed in this narrative review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.