ReviewSeminars in dialysis2017
A brief review of intradialytic hypotension with a focus on survival.
Review in Seminars in dialysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 132 citations in OpenAlex.
- Guideline
- Bradykinin BBMC nephrology · 2023Trial
- Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis.Jornal brasileiro de nefrologiaTrial
- Pressor Response Index During Blood Return as a Marker for Identifying Intradialytic Hypotension.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Article
- Article
- Personalized Hemodialysis Approaches in Frail Older Individuals.Geriatrics (Basel, Switzerland) · 2026Review
- Intra-Session recurrence in intradialytic hypotension prediction: evaluation implications and recurrence-aware modeling.Frontiers in digital health · 2026Article
- Updates in the management of intradialytic hypotension: Emerging strategies and innovations.World journal of nephrology · 2025Review
- Intermittent Infusion Hemodiafiltration: A Narrative Review of an Emerging Dialysis Modality.Toxins · 2025Review
- Patterns in Heart Rate Variability during Hemodialysis.Kidney360 · 2025Article
- Utility of Central Venous Oxygen Saturation Gradient in Predicting Mortality in Dialysis with Catheter Access.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Maternal Mortality due to Pregnancy-Related Acute Kidney Injury (PRAKI); A Study of the Epidemiological Factors and Possible Solutions.Journal of obstetrics and gynaecology of India · 2025Article
- Randomized Trial Demonstrating No Translocation of Intact Intestinal Bacteria During Hemodialysis or Hemodiafiltration.Kidney international reports · 2025Article
- Knowledge, Attitudes and Practices Toward Hypotension During Hemodialysis Among Nephrology and Hemodialysis Medical Staff: A Multi-Center Cross-Sectional Study.Journal of multidisciplinary healthcare · 2025Article
- Predialysis central arterial waveform and blood pressure changes during hemodialysis.Scientific reports · 2024Article
- Droxidopa for Management of Chronic Hypotension in Hemodialysis.Kidney international reports · 2024Article
- Intradialytic cardiovascular injury is lowest in high-volume haemodiafiltration: a randomized cross-over trial in four intermittent dialysis strategies.Clinical kidney journal · 2024Article
- Continuous Monitoring of Advanced Hemodynamic Parameters during Hemodialysis Demonstrated Early Variations in Patients Experiencing Intradialytic Hypotension.Biomedicines · 2024Article
- Effect of Electronic Moxibustion in Patients with IDH: A Randomized Crossover Pilot Study.International journal of general medicine · 2024Article
- Construction of an Early Alert System for Intradialytic Hypotension before Initiating Hemodialysis Based on Machine Learning.Kidney diseases (Basel, Switzerland) · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Intradialytic hypotension (IDH), a common complication of ultrafiltration during hemodialysis therapy, is associated with high mortality and morbidity. IDH, defined as a nadir systolic blood pressure of less than 90 mm Hg on more than 30% of treatments, is a relevant definition and is correlated with mortality. Risk factors for IDH include patient demographics, anti-hypertensive medication use, larger interdialytic weight gain, and dialysis prescription features as dialysate sodium, high ultrafiltration rate, and dialysate temperature. A high frequency of IDH events carries a substantial death risk. An ultrafiltration rate >10 mL/h/kg, and even more so >13 mL/h/kg, is highly predictive of cardiovascular and all-cause mortality. Evidence suggests that IDH causes acute reversible segmental myocardial hypoperfusion and contractile dysfunction (myocardial stunning), which can result in long-term loss of myocardial contractility, leading to premature death. IDH also has negative end-organ effects on the brain and gut, contributing to mortality through stroke, and endotoxin translocation with associated inflammation and protein-energy wasting. Given strong association of IDH and dialysis mortality, a paradigm shift to its approach is urgently needed. Randomized controlled trials are required to prospectively test drugs and monitoring devices which may reduce IDH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.