Evidence map›Paper›PMID 28661453›Full record

ArticleNutrients2017

LXRα Regulates Hepatic ChREBPα Activity and Lipogenesis upon Glucose, but Not Fructose Feeding in Mice.

Qiong Fan, Rikke C Nørgaard, Christian Bindesbøll, Christin Lucas, Knut Tomas Dalen, Eshrat Babaie, Harri M Itkonen, Jason Matthews, Hilde I Nebb, Line M Grønning-Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Liver X receptors and liver physiology.Biochimica et biophysica acta. Molecular basis of disease · 2021
    Review
  6. Review
  7. Role ofPhysiological reviews · 2021
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Qiong FanDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. qiong.fan@medisin.uio.no.
Rikke C NørgaardDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. r.c.norgaard@medisin.uio.no.
Christian BindesbøllDepartment of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. christian.bindesboll@medisin.uio.no.
Christin LucasDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. christin.lucas@medisin.uio.no.
Knut Tomas DalenDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. k.t.dalen@medisin.uio.no.
Eshrat BabaieCentre for Molecular Medicine Norway, University of Oslo, 0318 Oslo, Norway. eshrat.babaie@ncmm.uio.no.
Harri M ItkonenProstate Cancer Research Group, Centre for Molecular Medicine (Norway), University of Oslo and Oslo University Hospitals, 0318 Oslo, Norway. Harri_Itkonen@hms.harvard.edu.
Jason MatthewsDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. jason.matthews@medisin.uio.no.
Hilde I NebbDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. h.i.nebb@medisin.uio.no.
Line M Grønning-WangDepartment of Nutrition, Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. l.m.gronning-wang@medisin.uio.no.
University of Oslo · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver X receptors (LXRα/β) and carbohydrate response element-binding proteins (ChREBPα/β) are key players in the transcriptional control of hepatic

Indexed as

Animal FeedAnimal Nutritional Physiological PhenomenaAnimalsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsDietFood DeprivationFructoseGene Expression RegulationGlucoseLipogenesisLiver X ReceptorsMiceMice, KnockoutNuclear ProteinsSignal TransductionSterol Regulatory Element Binding Protein 1Basic Helix-Loop-Helix Leucine Zipper Transcription FactorsFructoseGlucoseLiver X ReceptorsMlxipl protein, mouseNr1h3 protein, mouseNuclear ProteinsSrebf1 protein, mouseSterol Regulatory Element Binding Protein 1Transcription FactorsChREBPde novo lipogenesis (DNL)LXRO-GlcNAc

Identifiers

PMID28661453
PMCPMC5537793
OpenAlexW2727209782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.