Evidence map›Paper›PMID 28661438›Full record

ArticleFoods (Basel, Switzerland)2017

Macular Carotenoid Supplementation Improves Visual Performance, Sleep Quality, and Adverse Physical Symptoms in Those with High Screen Time Exposure.

James M Stringham, Nicole T Stringham, Kevin J O'Brien

3 registry-linked trialsAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04779398 completednot on this mapstarted 2020, after this paper: background citation

Investigating Associations Between Chronic Electronic Device Blue Light Exposure, Dietary Xanthophyll Intake and Macular Pigment Density in Humans.

TypeobservationalSponsorThe University of QueenslandRan2020 to 2022Enrolled96ConditionsAge Related Macular Degeneration
NCT04779411 completednot on this mapstarted 2020, after this paper: background citation

Validation of a Lutein and Zeaxanthin Food Frequency Questionnaire, and an Electronic Device Use Questionnaire.

TypeobservationalSponsorThe University of QueenslandRan2020 to 2022Enrolled183ConditionsLutein and Zeaxanthin Dietary Intake, Age Related Macular Degeneration, Blue Light Exposure, Electronic Device UseArmsWeekly Food Frequency Questionnaire, Monthly Food Frequency Questionnaire, 24-Hour Diet Recall, Electronic Device Use Questionnaire, 24-Hour Electronic Device Use Diary
NCT06270680 early_phase1completednot on this mapstarted 2024, after this paper: background citation

Efficacy of Carotenoids on Blood Biomarkers Following A Collision Sport Athletes

TypeinterventionalSponsorPenn State UniversityRan2024 to 2024Enrolled31ConditionsHead Injury, CarotenoidsArmsVision Edge Pro, Placebo
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Is critical flicker-fusion frequency a valid measure of visual fatigue? A post-hoc analysis of a double-masked randomised controlled trial.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023
    Trial
  5. Review
  6. Eye Safety of Light-Emitting Diodes in Toys: The Results of Three Years of Market Surveillance.International journal of environmental research and public health · 2026
    Article
  7. Article
  8. Assessing the role of macular pigment optical volume in non-neovascular age-related macular degeneration: associations with rod-mediated dark adaptation and disease progression.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Observational
  9. Article
  10. Article
  11. The effects of lutein/ zeaxanthin (Lute-genFrontiers in nutrition · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James M StringhamNutritional Neuroscience Laboratory, Department of Psychology, University of Georgia, Athens, GA 30602, USA. jim.stringham@gmail.com.
Nicole T StringhamInterdisciplinary Neuroscience Program, Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602, USA. ntstringham@gmail.com.
Kevin J O'BrienVision Sciences Laboratory, Department of Psychology, University of Georgia, Athens, GA 30602, USA. Obrien.psych@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dramatic rise in the use of smartphones, tablets, and laptop computers over the past decade has raised concerns about potentially deleterious health effects of increased "screen time" (ST) and associated short-wavelength (blue) light exposure. We determined baseline associations and effects of 6 months' supplementation with the macular carotenoids (MC) lutein, zeaxanthin, and mesozeaxanthin on the blue-absorbing macular pigment (MP) and measures of sleep quality, visual performance, and physical indicators of excessive ST. Forty-eight healthy young adults with at least 6 h of daily near-field ST exposure participated in this placebo-controlled trial. Visual performance measures included contrast sensitivity, critical flicker fusion, disability glare, and photostress recovery. Physical indicators of excessive screen time and sleep quality were assessed via questionnaire. MP optical density (MPOD) was assessed via heterochromatic flicker photometry. At baseline, MPOD was correlated significantly with all visual performance measures (

Indexed as

computer vision syndromeluteinmacular pigmentmesozeaxanthinscreen timesleep qualityvisual performancezeaxanthin

Identifiers

PMID28661438
PMCPMC5532554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.